According to our (Global Info Research) latest study, the global Nitroglycerin API market size was valued at US$ 65.11 million in 2025 and is forecast to a readjusted size of US$ 93.59 million by 2032 with a CAGR of 5.4% during review period.
Nitroglycerin, also known as nitroglycerine, trinitroglycerin, nitro, glyceryl trinitrate, or 1,2,3-trinitroxypropane, is a dense, colorless, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester. This report focuses on nitroglycerin active pharmaceutical ingredient which is mainly use for intravenous, nitroglycerin patch and sublingual spray.In 2024, global Nitroglycerin API production reached approximately 243 MT, with an average global market price of around US$ 246.1 per Kg.The average gross profit margin of this product is 24%.
The global Nitroglycerin API market is shaped by a combination of medical, technological, and regulatory factors that collectively drive its steady yet specialized growth. One of the primary drivers is the consistent clinical demand for cardiovascular medications, particularly those addressing ischemic heart diseases such as angina pectoris and myocardial infarction. As the prevalence of cardiovascular diseases continues to rise globally, fueled by aging populations, lifestyle changes, and urbanization, the need for effective vasodilators remains persistent. Nitroglycerin, as a cornerstone therapeutic molecule with proven efficacy and safety, retains its essential role in emergency and chronic cardiac care. Furthermore, the diversification of dosage forms—including sublingual tablets, transdermal patches, and injectable formulations—has expanded the application scope of Nitroglycerin API, enabling flexible treatment approaches across both hospital and outpatient settings.
Technological advancements also serve as a critical driver for market development. Continuous improvements in synthesis technology, purification methods, and stabilization processes have significantly enhanced the safety and yield of Nitroglycerin API production. Modern manufacturing facilities now employ closed systems, microreactor technologies, and real-time monitoring to mitigate explosion risks and ensure product consistency. In addition, regulatory emphasis on Good Manufacturing Practice (GMP) and environmental protection has encouraged the industry to adopt greener and safer production routes. The integration of advanced analytical instruments for quality control has further strengthened the reliability of supply chains, while strategic partnerships between API producers and finished dosage manufacturers have contributed to more efficient global distribution networks.
However, the Nitroglycerin API industry faces a number of structural and operational challenges. The compound’s inherent instability and explosive potential make its production extremely sensitive, requiring specialized facilities, skilled personnel, and stringent safety oversight. This significantly raises the barrier to entry, limiting the number of global suppliers and leading to concentration risk. Moreover, strict government regulations regarding the handling and export of nitrate-based chemicals impose compliance burdens on manufacturers, especially in regions with heightened control of dual-use substances. The growing preference for novel anti-anginal and cardiovascular drugs has also introduced competitive pressure, gradually reducing the relative market share of traditional nitroglycerin-based therapies in some developed regions. Environmental sustainability adds another layer of complexity, as nitration processes can generate hazardous waste if not properly managed. Consequently, the future growth of the Nitroglycerin API market will depend on the industry’s ability to balance safety, regulatory compliance, and technological innovation while sustaining cost-effectiveness and global supply reliability.
This report is a detailed and comprehensive analysis for global Nitroglycerin API market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global Nitroglycerin API market size and forecasts, in consumption value ($ Million), sales quantity (Tons), and average selling prices (USD/Kg), 2021-2032
Global Nitroglycerin API market size and forecasts by region and country, in consumption value ($ Million), sales quantity (Tons), and average selling prices (USD/Kg), 2021-2032
Global Nitroglycerin API market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (Tons), and average selling prices (USD/Kg), 2021-2032
Global Nitroglycerin API market shares of main players, shipments in revenue ($ Million), sales quantity (Tons), and ASP (USD/Kg), 2021-2026
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for Nitroglycerin API
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global Nitroglycerin API market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Axplora (Novasep), Copperhead Chemical, SD Sinepharm, Lesheng Phamra, Bharat Pharma, Beijing Yimin, Dipharma, Dorsa Pharmaceutical, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market Segmentation
Nitroglycerin API market is split by Type and by Application. For the period 2021-2032, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Type
10% NG
2% NG
Other
Market segment by Pharmacopeial Grade
USP
EP
ChP
Market segment by Sales Channel
Online
Offline
Market segment by Application
Intravenous
Oral
Other
Major players covered
Axplora (Novasep)
Copperhead Chemical
SD Sinepharm
Lesheng Phamra
Bharat Pharma
Beijing Yimin
Dipharma
Dorsa Pharmaceutical
Market segment by region, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe Nitroglycerin API product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of Nitroglycerin API, with price, sales quantity, revenue, and global market share of Nitroglycerin API from 2021 to 2026.
Chapter 3, the Nitroglycerin API competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the Nitroglycerin API breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2021 to 2032.
Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2021 to 2032.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2021 to 2026.and Nitroglycerin API market forecast, by regions, by Type, and by Application, with sales and revenue, from 2027 to 2032.
Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
Chapter 13, the key raw materials and key suppliers, and industry chain of Nitroglycerin API.
Chapter 14 and 15, to describe Nitroglycerin API sales channel, distributors, customers, research findings and conclusion.
Summary:
Get latest Market Research Reports on Nitroglycerin API. Industry analysis & Market Report on Nitroglycerin API is a syndicated market report, published as Global Nitroglycerin API Market 2026 by Manufacturers, Regions, Type and Application, Forecast to 2032. It is complete Research Study and Industry Analysis of Nitroglycerin API market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.