Report Detail

According to our (Global Info Research) latest study, the global mRNA Vaccine Core Enzyme market size was valued at US$ 2020 million in 2025 and is forecast to a readjusted size of US$ 1703 million by 2032 with a CAGR of -2.4% during review period.
mRNA-vaccines can efficiently activate both components of the immune system, i.e., T-cell and humoral responses. The essential advantage of mRNA vaccines includes fast, inexpensive, scalable and uniform production providing a large output of desirable products in vitro. Synthesis and purification processes significantly simplify the process technology of mRNA drugs with injectable purity. Thus, mRNA production via in vitro transcription is more advantageous as compared with DNA-vaccines since it is a chemical process without the use of cells. mRNA techniques make it possible to pass all the phases of vaccine development much faster in comparison with the production of vaccines based on inactivated viruses or recombinant proteins. This property is critically important when designing vaccines against viral pathogens as the main problem of disease control includes a time gap between an epidemic and vaccine development. mRNA vaccine core enzyme is the key raw material in the production of mRNA vaccine and drugs.
The core manufacturers of mRNA Vaccine Core Enzyme mainly include Thermo Fisher, NEB, TriLink Bio Technologies, Merck, etc. The top four companies in the industry account for about 49% of the market. North America is the largest market, accounting for about 38% of the global market share. In terms of product type, Capping Enzyme have the largest market share of about 25%. From an application perspective, Biopharmaceutical Companies account for the largest share at around 84%.
This report is a detailed and comprehensive analysis for global mRNA Vaccine Core Enzyme market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Enzyme Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global mRNA Vaccine Core Enzyme market size and forecasts, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2021-2032
Global mRNA Vaccine Core Enzyme market size and forecasts by region and country, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2021-2032
Global mRNA Vaccine Core Enzyme market size and forecasts, by Enzyme Type and by Application, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2021-2032
Global mRNA Vaccine Core Enzyme market shares of main players, shipments in revenue ($ Million), sales quantity (K Units), and ASP (US$/Unit), 2021-2026
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for mRNA Vaccine Core Enzyme
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global mRNA Vaccine Core Enzyme market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Thermo Fisher, NEB, TriLink Bio Technologies, Merck, Aldevron, Qiagen N.V., Promega, Roche CustomBiotech, Takara Bio Inc., Novoprotein, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market Segmentation
mRNA Vaccine Core Enzyme market is split by Enzyme Type and by Application. For the period 2021-2032, the growth among segments provides accurate calculations and forecasts for consumption value by Enzyme Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Enzyme Type
Capping Enzyme
2'-O-Methyltransferase
Inorganic Pyrophosphatase
Poly (A) Polymerase
Rnase Inhibitor
RNA Polymerase
Restriction Enzyme
Dnase I
Others
Market segment by Application
Biopharmaceutical Companies
Academic and Research Institutions
Major players covered
Thermo Fisher
NEB
TriLink Bio Technologies
Merck
Aldevron
Qiagen N.V.
Promega
Roche CustomBiotech
Takara Bio Inc.
Novoprotein
Vazyme
Hongene Biotech Corporatio
Yeasen Biotechnology
Market segment by region, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe mRNA Vaccine Core Enzyme product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of mRNA Vaccine Core Enzyme, with price, sales quantity, revenue, and global market share of mRNA Vaccine Core Enzyme from 2021 to 2026.
Chapter 3, the mRNA Vaccine Core Enzyme competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the mRNA Vaccine Core Enzyme breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2021 to 2032.
Chapter 5 and 6, to segment the sales by Enzyme Type and by Application, with sales market share and growth rate by Enzyme Type, by Application, from 2021 to 2032.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2021 to 2026.and mRNA Vaccine Core Enzyme market forecast, by regions, by Enzyme Type, and by Application, with sales and revenue, from 2027 to 2032.
Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
Chapter 13, the key raw materials and key suppliers, and industry chain of mRNA Vaccine Core Enzyme.
Chapter 14 and 15, to describe mRNA Vaccine Core Enzyme sales channel, distributors, customers, research findings and conclusion.


1 Market Overview

  • 1.1 Product Overview and Scope
  • 1.2 Market Estimation Caveats and Base Year
  • 1.3 Market Analysis by Enzyme Type
    • 1.3.1 Overview: Global mRNA Vaccine Core Enzyme Consumption Value by Enzyme Type: 2021 Versus 2025 Versus 2032
    • 1.3.2 Capping Enzyme
    • 1.3.3 2'-O-Methyltransferase
    • 1.3.4 Inorganic Pyrophosphatase
    • 1.3.5 Poly (A) Polymerase
    • 1.3.6 Rnase Inhibitor
    • 1.3.7 RNA Polymerase
    • 1.3.8 Restriction Enzyme
    • 1.3.9 Dnase I
    • 1.3.10 Others
  • 1.4 Market Analysis by Application
    • 1.4.1 Overview: Global mRNA Vaccine Core Enzyme Consumption Value by Application: 2021 Versus 2025 Versus 2032
    • 1.4.2 Biopharmaceutical Companies
    • 1.4.3 Academic and Research Institutions
  • 1.5 Global mRNA Vaccine Core Enzyme Market Size & Forecast
    • 1.5.1 Global mRNA Vaccine Core Enzyme Consumption Value (2021 & 2025 & 2032)
    • 1.5.2 Global mRNA Vaccine Core Enzyme Sales Quantity (2021-2032)
    • 1.5.3 Global mRNA Vaccine Core Enzyme Average Price (2021-2032)

2 Manufacturers Profiles

  • 2.1 Thermo Fisher
    • 2.1.1 Thermo Fisher Details
    • 2.1.2 Thermo Fisher Major Business
    • 2.1.3 Thermo Fisher mRNA Vaccine Core Enzyme Product and Services
    • 2.1.4 Thermo Fisher mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.1.5 Thermo Fisher Recent Developments/Updates
  • 2.2 NEB
    • 2.2.1 NEB Details
    • 2.2.2 NEB Major Business
    • 2.2.3 NEB mRNA Vaccine Core Enzyme Product and Services
    • 2.2.4 NEB mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.2.5 NEB Recent Developments/Updates
  • 2.3 TriLink Bio Technologies
    • 2.3.1 TriLink Bio Technologies Details
    • 2.3.2 TriLink Bio Technologies Major Business
    • 2.3.3 TriLink Bio Technologies mRNA Vaccine Core Enzyme Product and Services
    • 2.3.4 TriLink Bio Technologies mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.3.5 TriLink Bio Technologies Recent Developments/Updates
  • 2.4 Merck
    • 2.4.1 Merck Details
    • 2.4.2 Merck Major Business
    • 2.4.3 Merck mRNA Vaccine Core Enzyme Product and Services
    • 2.4.4 Merck mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.4.5 Merck Recent Developments/Updates
  • 2.5 Aldevron
    • 2.5.1 Aldevron Details
    • 2.5.2 Aldevron Major Business
    • 2.5.3 Aldevron mRNA Vaccine Core Enzyme Product and Services
    • 2.5.4 Aldevron mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.5.5 Aldevron Recent Developments/Updates
  • 2.6 Qiagen N.V.
    • 2.6.1 Qiagen N.V. Details
    • 2.6.2 Qiagen N.V. Major Business
    • 2.6.3 Qiagen N.V. mRNA Vaccine Core Enzyme Product and Services
    • 2.6.4 Qiagen N.V. mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.6.5 Qiagen N.V. Recent Developments/Updates
  • 2.7 Promega
    • 2.7.1 Promega Details
    • 2.7.2 Promega Major Business
    • 2.7.3 Promega mRNA Vaccine Core Enzyme Product and Services
    • 2.7.4 Promega mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.7.5 Promega Recent Developments/Updates
  • 2.8 Roche CustomBiotech
    • 2.8.1 Roche CustomBiotech Details
    • 2.8.2 Roche CustomBiotech Major Business
    • 2.8.3 Roche CustomBiotech mRNA Vaccine Core Enzyme Product and Services
    • 2.8.4 Roche CustomBiotech mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.8.5 Roche CustomBiotech Recent Developments/Updates
  • 2.9 Takara Bio Inc.
    • 2.9.1 Takara Bio Inc. Details
    • 2.9.2 Takara Bio Inc. Major Business
    • 2.9.3 Takara Bio Inc. mRNA Vaccine Core Enzyme Product and Services
    • 2.9.4 Takara Bio Inc. mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.9.5 Takara Bio Inc. Recent Developments/Updates
  • 2.10 Novoprotein
    • 2.10.1 Novoprotein Details
    • 2.10.2 Novoprotein Major Business
    • 2.10.3 Novoprotein mRNA Vaccine Core Enzyme Product and Services
    • 2.10.4 Novoprotein mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.10.5 Novoprotein Recent Developments/Updates
  • 2.11 Vazyme
    • 2.11.1 Vazyme Details
    • 2.11.2 Vazyme Major Business
    • 2.11.3 Vazyme mRNA Vaccine Core Enzyme Product and Services
    • 2.11.4 Vazyme mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.11.5 Vazyme Recent Developments/Updates
  • 2.12 Hongene Biotech Corporatio
    • 2.12.1 Hongene Biotech Corporatio Details
    • 2.12.2 Hongene Biotech Corporatio Major Business
    • 2.12.3 Hongene Biotech Corporatio mRNA Vaccine Core Enzyme Product and Services
    • 2.12.4 Hongene Biotech Corporatio mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.12.5 Hongene Biotech Corporatio Recent Developments/Updates
  • 2.13 Yeasen Biotechnology
    • 2.13.1 Yeasen Biotechnology Details
    • 2.13.2 Yeasen Biotechnology Major Business
    • 2.13.3 Yeasen Biotechnology mRNA Vaccine Core Enzyme Product and Services
    • 2.13.4 Yeasen Biotechnology mRNA Vaccine Core Enzyme Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2021-2026)
    • 2.13.5 Yeasen Biotechnology Recent Developments/Updates

3 Competitive Environment: mRNA Vaccine Core Enzyme by Manufacturer

  • 3.1 Global mRNA Vaccine Core Enzyme Sales Quantity by Manufacturer (2021-2026)
  • 3.2 Global mRNA Vaccine Core Enzyme Revenue by Manufacturer (2021-2026)
  • 3.3 Global mRNA Vaccine Core Enzyme Average Price by Manufacturer (2021-2026)
  • 3.4 Market Share Analysis (2025)
    • 3.4.1 Producer Shipments of mRNA Vaccine Core Enzyme by Manufacturer Revenue ($MM) and Market Share (%): 2025
    • 3.4.2 Top 3 mRNA Vaccine Core Enzyme Manufacturer Market Share in 2025
    • 3.4.3 Top 6 mRNA Vaccine Core Enzyme Manufacturer Market Share in 2025
  • 3.5 mRNA Vaccine Core Enzyme Market: Overall Company Footprint Analysis
    • 3.5.1 mRNA Vaccine Core Enzyme Market: Region Footprint
    • 3.5.2 mRNA Vaccine Core Enzyme Market: Company Product Type Footprint
    • 3.5.3 mRNA Vaccine Core Enzyme Market: Company Product Application Footprint
  • 3.6 New Market Entrants and Barriers to Market Entry
  • 3.7 Mergers, Acquisition, Agreements, and Collaborations

4 Consumption Analysis by Region

  • 4.1 Global mRNA Vaccine Core Enzyme Market Size by Region
    • 4.1.1 Global mRNA Vaccine Core Enzyme Sales Quantity by Region (2021-2032)
    • 4.1.2 Global mRNA Vaccine Core Enzyme Consumption Value by Region (2021-2032)
    • 4.1.3 Global mRNA Vaccine Core Enzyme Average Price by Region (2021-2032)
  • 4.2 North America mRNA Vaccine Core Enzyme Consumption Value (2021-2032)
  • 4.3 Europe mRNA Vaccine Core Enzyme Consumption Value (2021-2032)
  • 4.4 Asia-Pacific mRNA Vaccine Core Enzyme Consumption Value (2021-2032)
  • 4.5 South America mRNA Vaccine Core Enzyme Consumption Value (2021-2032)
  • 4.6 Middle East & Africa mRNA Vaccine Core Enzyme Consumption Value (2021-2032)

5 Market Segment by Enzyme Type

  • 5.1 Global mRNA Vaccine Core Enzyme Sales Quantity by Enzyme Type (2021-2032)
  • 5.2 Global mRNA Vaccine Core Enzyme Consumption Value by Enzyme Type (2021-2032)
  • 5.3 Global mRNA Vaccine Core Enzyme Average Price by Enzyme Type (2021-2032)

6 Market Segment by Application

  • 6.1 Global mRNA Vaccine Core Enzyme Sales Quantity by Application (2021-2032)
  • 6.2 Global mRNA Vaccine Core Enzyme Consumption Value by Application (2021-2032)
  • 6.3 Global mRNA Vaccine Core Enzyme Average Price by Application (2021-2032)

7 North America

  • 7.1 North America mRNA Vaccine Core Enzyme Sales Quantity by Enzyme Type (2021-2032)
  • 7.2 North America mRNA Vaccine Core Enzyme Sales Quantity by Application (2021-2032)
  • 7.3 North America mRNA Vaccine Core Enzyme Market Size by Country
    • 7.3.1 North America mRNA Vaccine Core Enzyme Sales Quantity by Country (2021-2032)
    • 7.3.2 North America mRNA Vaccine Core Enzyme Consumption Value by Country (2021-2032)
    • 7.3.3 United States Market Size and Forecast (2021-2032)
    • 7.3.4 Canada Market Size and Forecast (2021-2032)
    • 7.3.5 Mexico Market Size and Forecast (2021-2032)

8 Europe

  • 8.1 Europe mRNA Vaccine Core Enzyme Sales Quantity by Enzyme Type (2021-2032)
  • 8.2 Europe mRNA Vaccine Core Enzyme Sales Quantity by Application (2021-2032)
  • 8.3 Europe mRNA Vaccine Core Enzyme Market Size by Country
    • 8.3.1 Europe mRNA Vaccine Core Enzyme Sales Quantity by Country (2021-2032)
    • 8.3.2 Europe mRNA Vaccine Core Enzyme Consumption Value by Country (2021-2032)
    • 8.3.3 Germany Market Size and Forecast (2021-2032)
    • 8.3.4 France Market Size and Forecast (2021-2032)
    • 8.3.5 United Kingdom Market Size and Forecast (2021-2032)
    • 8.3.6 Russia Market Size and Forecast (2021-2032)
    • 8.3.7 Italy Market Size and Forecast (2021-2032)

9 Asia-Pacific

  • 9.1 Asia-Pacific mRNA Vaccine Core Enzyme Sales Quantity by Enzyme Type (2021-2032)
  • 9.2 Asia-Pacific mRNA Vaccine Core Enzyme Sales Quantity by Application (2021-2032)
  • 9.3 Asia-Pacific mRNA Vaccine Core Enzyme Market Size by Region
    • 9.3.1 Asia-Pacific mRNA Vaccine Core Enzyme Sales Quantity by Region (2021-2032)
    • 9.3.2 Asia-Pacific mRNA Vaccine Core Enzyme Consumption Value by Region (2021-2032)
    • 9.3.3 China Market Size and Forecast (2021-2032)
    • 9.3.4 Japan Market Size and Forecast (2021-2032)
    • 9.3.5 South Korea Market Size and Forecast (2021-2032)
    • 9.3.6 India Market Size and Forecast (2021-2032)
    • 9.3.7 Southeast Asia Market Size and Forecast (2021-2032)
    • 9.3.8 Australia Market Size and Forecast (2021-2032)

10 South America

  • 10.1 South America mRNA Vaccine Core Enzyme Sales Quantity by Enzyme Type (2021-2032)
  • 10.2 South America mRNA Vaccine Core Enzyme Sales Quantity by Application (2021-2032)
  • 10.3 South America mRNA Vaccine Core Enzyme Market Size by Country
    • 10.3.1 South America mRNA Vaccine Core Enzyme Sales Quantity by Country (2021-2032)
    • 10.3.2 South America mRNA Vaccine Core Enzyme Consumption Value by Country (2021-2032)
    • 10.3.3 Brazil Market Size and Forecast (2021-2032)
    • 10.3.4 Argentina Market Size and Forecast (2021-2032)

11 Middle East & Africa

  • 11.1 Middle East & Africa mRNA Vaccine Core Enzyme Sales Quantity by Enzyme Type (2021-2032)
  • 11.2 Middle East & Africa mRNA Vaccine Core Enzyme Sales Quantity by Application (2021-2032)
  • 11.3 Middle East & Africa mRNA Vaccine Core Enzyme Market Size by Country
    • 11.3.1 Middle East & Africa mRNA Vaccine Core Enzyme Sales Quantity by Country (2021-2032)
    • 11.3.2 Middle East & Africa mRNA Vaccine Core Enzyme Consumption Value by Country (2021-2032)
    • 11.3.3 Turkey Market Size and Forecast (2021-2032)
    • 11.3.4 Egypt Market Size and Forecast (2021-2032)
    • 11.3.5 Saudi Arabia Market Size and Forecast (2021-2032)
    • 11.3.6 South Africa Market Size and Forecast (2021-2032)

12 Market Dynamics

  • 12.1 mRNA Vaccine Core Enzyme Market Drivers
  • 12.2 mRNA Vaccine Core Enzyme Market Restraints
  • 12.3 mRNA Vaccine Core Enzyme Trends Analysis
  • 12.4 Porters Five Forces Analysis
    • 12.4.1 Threat of New Entrants
    • 12.4.2 Bargaining Power of Suppliers
    • 12.4.3 Bargaining Power of Buyers
    • 12.4.4 Threat of Substitutes
    • 12.4.5 Competitive Rivalry

13 Raw Material and Industry Chain

  • 13.1 Raw Material of mRNA Vaccine Core Enzyme and Key Manufacturers
  • 13.2 Manufacturing Costs Percentage of mRNA Vaccine Core Enzyme
  • 13.3 mRNA Vaccine Core Enzyme Production Process
  • 13.4 Industry Value Chain Analysis

14 Shipments by Distribution Channel

  • 14.1 Sales Channel
    • 14.1.1 Direct to End-User
    • 14.1.2 Distributors
  • 14.2 mRNA Vaccine Core Enzyme Typical Distributors
  • 14.3 mRNA Vaccine Core Enzyme Typical Customers

15 Research Findings and Conclusion

    16 Appendix

    • 16.1 Methodology
    • 16.2 Research Process and Data Source

    Summary:
    Get latest Market Research Reports on mRNA Vaccine Core Enzyme. Industry analysis & Market Report on mRNA Vaccine Core Enzyme is a syndicated market report, published as Global mRNA Vaccine Core Enzyme Market 2026 by Manufacturers, Regions, Type and Application, Forecast to 2032. It is complete Research Study and Industry Analysis of mRNA Vaccine Core Enzyme market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.

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