Report Detail

Pharma & Healthcare Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 - Pipeline Review, H2 2019

  • RnM3784277
  • |
  • 26 September, 2019
  • |
  • Global
  • |
  • 76 Pages
  • |
  • Global Markets Direct
  • |
  • Pharma & Healthcare

Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 - Pipeline Review, H2 2019

Summary

Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) pipeline Target constitutes close to 20 molecules. Out of which approximately 16 molecules are developed by companies and remaining by the universities/institutes. The latest report Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 - Pipeline Review, H2 2019, outlays comprehensive information on the Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) - Induced myeloid leukemia cell differentiation protein Mcl-1 also known as Bcl-2-like protein 3 or bcl-2-related protein EATS/Mcl1 is a protein encoded by the MCL1 gene. It is involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. It mediates its effects by interactions with a number of other regulators of apoptosis. The molecules developed by companies in Phase II, Phase I, Preclinical and Discovery stages are 1, 5, 3 and 7 respectively.

Similarly, the universities portfolio in Preclinical and Discovery stages comprises 2 and 2 molecules, respectively. Report covers products from therapy areas Oncology and Infectious Disease which include indications Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia), Multiple Myeloma (Kahler Disease), Non-Hodgkin Lymphoma, Refractory Multiple Myeloma, Relapsed Multiple Myeloma, Breast Cancer, Diffuse Large B-Cell Lymphoma, Myelodysplastic Syndrome, Pancreatic Cancer, Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia, Solid Tumor, Acute Lymphocytic Leukemia (ALL, Acute Lymphoblastic Leukemia), Blood Cancer, Chronic Lymphocytic Leukemia (CLL), Colorectal Cancer, Head And Neck Cancer, Hematological Tumor, Hypopharyngeal Cancer, Laryngeal Cancer, Malignant Mesothelioma, Melanoma, Methicillin-Resistant Staphylococcus aureus (MRSA) Infections, Non-Small Cell Lung Cancer, Ovarian Cancer, Prostate Cancer, Refractory Chronic Lymphocytic Leukemia (CLL), Relapsed Chronic Lymphocytic Leukemia (CLL), T-Cell Lymphomas and Triple-Negative Breast Cancer (TNBC).

Furthermore, this report also reviews key players involved in Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape for Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1)
- The report reviews Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) targeted therapeutics and enlists all their major and minor projects
- The report assesses Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope


Table of Contents

    List of Tables

      List of Figures

        Introduction

          Global Markets Direct Report Coverage

            Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) - Overview

              Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) - Therapeutics Development

                Products under Development by Stage of Development

                  Products under Development by Therapy Area

                    Products under Development by Indication

                      Products under Development by Companies

                        Products under Development by Universities/Institutes

                          Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) - Therapeutics Assessment

                            Assessment by Mechanism of Action

                              Assessment by Route of Administration

                                Assessment by Molecule Type

                                  Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) - Companies Involved in Therapeutics Development

                                    AbbVie Inc

                                      Aileron Therapeutics Inc

                                        Amgen Inc

                                          AstraZeneca Plc

                                            Boehringer Ingelheim International GmbH

                                              Canget BioTekpharma LLC

                                                Circle Pharma Inc

                                                  Complix NV

                                                    InteRNA Technologies BV

                                                      Les Laboratoires Servier SAS

                                                        Pfizer Inc

                                                          X-Rx Inc

                                                            Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) - Drug Profiles

                                                              AMG-176 - Drug Profile

                                                                Product Description

                                                                  Mechanism Of Action

                                                                    R&D Progress

                                                                      AMG-397 - Drug Profile

                                                                        Product Description

                                                                          Mechanism Of Action

                                                                            R&D Progress

                                                                              AT-101 - Drug Profile

                                                                                Product Description

                                                                                  Mechanism Of Action

                                                                                    R&D Progress

                                                                                      AZD-5991 - Drug Profile

                                                                                        Product Description

                                                                                          Mechanism Of Action

                                                                                            R&D Progress

                                                                                              FL-118 - Drug Profile

                                                                                                Product Description

                                                                                                  Mechanism Of Action

                                                                                                    R&D Progress

                                                                                                      INT-1B3 - Drug Profile

                                                                                                        Product Description

                                                                                                          Mechanism Of Action

                                                                                                            R&D Progress

                                                                                                              Recombinant Proteins to Inhibit MCL-1 for Oncology - Drug Profile

                                                                                                                Product Description

                                                                                                                  Mechanism Of Action

                                                                                                                    R&D Progress

                                                                                                                      S-63845 - Drug Profile

                                                                                                                        Product Description

                                                                                                                          Mechanism Of Action

                                                                                                                            R&D Progress

                                                                                                                              S-64315 - Drug Profile

                                                                                                                                Product Description

                                                                                                                                  Mechanism Of Action

                                                                                                                                    R&D Progress

                                                                                                                                      Small Molecules to Inhibit Mcl-1 and Bcl-xL for Oncology and MRSA Infections - Drug Profile

                                                                                                                                        Product Description

                                                                                                                                          Mechanism Of Action

                                                                                                                                            R&D Progress

                                                                                                                                              Small Molecules to Inhibit MCL-1 for Breast Cancer - Drug Profile

                                                                                                                                                Product Description

                                                                                                                                                  Mechanism Of Action

                                                                                                                                                    R&D Progress

                                                                                                                                                      Small Molecules to Inhibit MCL-1 for Oncology - Drug Profile

                                                                                                                                                        Product Description

                                                                                                                                                          Mechanism Of Action

                                                                                                                                                            R&D Progress

                                                                                                                                                              Small Molecules to Inhibit MCL-1 for Oncology - Drug Profile

                                                                                                                                                                Product Description

                                                                                                                                                                  Mechanism Of Action

                                                                                                                                                                    R&D Progress

                                                                                                                                                                      Small Molecules to Inhibit MCL1 for Multiple Myeloma - Drug Profile

                                                                                                                                                                        Product Description

                                                                                                                                                                          Mechanism Of Action

                                                                                                                                                                            R&D Progress

                                                                                                                                                                              Small Molecules to Inhibit MCL1 for Oncology - Drug Profile

                                                                                                                                                                                Product Description

                                                                                                                                                                                  Mechanism Of Action

                                                                                                                                                                                    R&D Progress

                                                                                                                                                                                      Small Molecules to Inhibit MCL1 for Oncology - Drug Profile

                                                                                                                                                                                        Product Description

                                                                                                                                                                                          Mechanism Of Action

                                                                                                                                                                                            R&D Progress

                                                                                                                                                                                              Synthetic Peptides to Inhibit MCL1 and BCL1 for Solid Tumors and Liquid Tumors - Drug Profile

                                                                                                                                                                                                Product Description

                                                                                                                                                                                                  Mechanism Of Action

                                                                                                                                                                                                    R&D Progress

                                                                                                                                                                                                      Synthetic Peptides to Inhibit MCL1 for Oncology - Drug Profile

                                                                                                                                                                                                        Product Description

                                                                                                                                                                                                          Mechanism Of Action

                                                                                                                                                                                                            R&D Progress

                                                                                                                                                                                                              Synthetic Peptides to Inhibit MCL1 for Oncology - Drug Profile

                                                                                                                                                                                                                Product Description

                                                                                                                                                                                                                  Mechanism Of Action

                                                                                                                                                                                                                    R&D Progress

                                                                                                                                                                                                                      UMI-77 - Drug Profile

                                                                                                                                                                                                                        Product Description

                                                                                                                                                                                                                          Mechanism Of Action

                                                                                                                                                                                                                            R&D Progress

                                                                                                                                                                                                                              Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) - Dormant Products

                                                                                                                                                                                                                                Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 (Bcl 2 Like Protein 3 or Bcl 2 Related Protein EAT/Mcl1 or BCL2L3 or MCL1) - Product Development Milestones

                                                                                                                                                                                                                                  Featured News & Press Releases

                                                                                                                                                                                                                                    Mar 25, 2019: InteRNA appoints Andrea van Elsas, Ph.D. to Scientific Advisory Board

                                                                                                                                                                                                                                      Feb 28, 2019: Amgen highlights progress of innovative early oncology pipeline including AMG-176 new data at AACR 2019

                                                                                                                                                                                                                                        Nov 27, 2018: AstraZeneca to present on its multiple myeloma drug candidate AZD5991 at 2018 American Society of Hematology Annual Meeting

                                                                                                                                                                                                                                          Oct 12, 2018: New model mimics human tumours for accurate testing of cancer drugs

                                                                                                                                                                                                                                            Oct 01, 2018: InteRNA presents expanded preclinical proof-of-concept data on lead oncology development candidate INT-1B3 at the 14th Annual OTS Meeting

                                                                                                                                                                                                                                              Apr 18, 2018: InteRNA Demonstrates Preclinical Proof-of-Concept for Lead microRNA Candidate INT-1B3 in a Range of Cancer Models at 2018 AACR Annual Meeting

                                                                                                                                                                                                                                                Apr 09, 2018: Amgen To Present New Pre-Clinical Data Showcasing Robust Approach To Evaluating Potential Anti-Cancer Therapies At AACR 2018

                                                                                                                                                                                                                                                  Dec 14, 2017: Complix receives €0.5 million grant to further develop its pipeline of proprietary Cell Penetrating Alphabodies against intracellular cancer targets

                                                                                                                                                                                                                                                    Aug 03, 2017: Targeting Cancers Achilles Heel To Improve Breast Cancer Treatment

                                                                                                                                                                                                                                                      Mar 31, 2017: Amgen To Highlight New Preclinical Data At The American Association For Cancer Research (AACR) Annual Meeting

                                                                                                                                                                                                                                                        Oct 20, 2016: New compound shows promise in treating multiple human cancers

                                                                                                                                                                                                                                                          Oct 13, 2016: Ascentage Pharma takes a leading position in novel drug development targeting dual pathways of apoptosis and autophagy

                                                                                                                                                                                                                                                            Apr 28, 2015: Camptothecin Analog FL118 Can Overcome Treatment Resistance, Outperform Approved Therapies

                                                                                                                                                                                                                                                              Dec 15, 2014: Roswell Park Study Suggests Additional Applications for FL118 as Personalized Therapy for Cancer

                                                                                                                                                                                                                                                                Dec 31, 2013: Scientists Identify Key Structural Qualities that Distinguish Novel Anticancer Agent

                                                                                                                                                                                                                                                                  Appendix

                                                                                                                                                                                                                                                                    Methodology

                                                                                                                                                                                                                                                                      Coverage

                                                                                                                                                                                                                                                                        Secondary Research

                                                                                                                                                                                                                                                                          Primary Research

                                                                                                                                                                                                                                                                            Expert Panel Validation

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                                                                                                                                                                                                                                                                                Get latest Market Research Reports on Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1. Industry analysis & Market Report on Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 is a syndicated market report, published as Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 - Pipeline Review, H2 2019. It is complete Research Study and Industry Analysis of Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.

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