Report Detail

Pharma & Healthcare Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha - Pipeline Review, H2 2019

  • RnM3784278
  • |
  • 26 September, 2019
  • |
  • Global
  • |
  • 73 Pages
  • |
  • Global Markets Direct
  • |
  • Pharma & Healthcare

Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha - Pipeline Review, H2 2019

Summary

Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Granulocyte macrophage colony stimulating factor receptor subunit alpha also known as CD116 is a receptor for granulocyte macrophage colony-stimulating factor. It is a member of the cytokine family of receptors. It plays an important role in controls the production, differentiation, and function of granulocytes and macrophages.

Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) pipeline Target constitutes close to 11 molecules. Out of which approximately 9 molecules are developed by companies and remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I and Preclinical stages are 2, 2, 1 and 4 respectively. Similarly, the universities portfolio in Phase I and Preclinical stages comprises 1 and 1 molecules, respectively.

Report covers products from therapy areas Oncology, Central Nervous System, Respiratory, Infectious Disease, Toxicology, Dermatology, Gastrointestinal and Hematological Disorders which include indications Melanoma, Alzheimer's Disease, Lung Disease, Metastatic Hormone Refractory (Castration Resistant, Androgen-Independent) Prostate Cancer, Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome), Acute Respiratory Distress Syndrome, Appendicitis, Chemotherapy Effects, Chemotherapy Induced Neutropenia, Crohn's Disease (Regional Enteritis), Epithelial Ovarian Cancer, Lung Infections, Lung Injury, Malignant Pleural Mesothelioma, Metastatic Colorectal Cancer, Mild Cognitive Impairment, Mycobacterium Infections, Neurology, Peritoneal Cancer, Peritonitis, Radiation Injury, Respiratory Syncytial Virus (RSV) Infections, Skin Ulcers and Wounds.

The latest report Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha - Pipeline Review, H2 2019, outlays comprehensive information on the Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews key players involved in Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) targeted therapeutics development with respective active and dormant or discontinued projects.

The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape for Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA)
- The report reviews Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) targeted therapeutics and enlists all their major and minor projects
- The report assesses Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope


Table of Contents

    List of Tables

      List of Figures

        Introduction

          Global Markets Direct Report Coverage

            Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Overview

              Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Therapeutics Development

                Products under Development by Stage of Development

                  Products under Development by Therapy Area

                    Products under Development by Indication

                      Products under Development by Companies

                        Products under Development by Universities/Institutes

                          Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Therapeutics Assessment

                            Assessment by Mechanism of Action

                              Assessment by Route of Administration

                                Assessment by Molecule Type

                                  Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Companies Involved in Therapeutics Development

                                    Aduro BioTech Inc

                                      Bolder Biotechnology Inc

                                        Celdara Medical LLC

                                          Profarma

                                            Savara Inc

                                              Targovax ASA

                                                XL-protein GmbH

                                                  Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Drug Profiles

                                                    BBT-007 - Drug Profile

                                                      Product Description

                                                        Mechanism Of Action

                                                          R&D Progress

                                                            CMJG-01 - Drug Profile

                                                              Product Description

                                                                Mechanism Of Action

                                                                  R&D Progress

                                                                    GVAX Vaccine - Drug Profile

                                                                      Product Description

                                                                        Mechanism Of Action

                                                                          R&D Progress

                                                                            molgramostim - Drug Profile

                                                                              Product Description

                                                                                Mechanism Of Action

                                                                                  R&D Progress

                                                                                    molgramostim - Drug Profile

                                                                                      Product Description

                                                                                        Mechanism Of Action

                                                                                          R&D Progress

                                                                                            molgramostim - Drug Profile

                                                                                              Product Description

                                                                                                Mechanism Of Action

                                                                                                  R&D Progress

                                                                                                    ONCOS-102 - Drug Profile

                                                                                                      Product Description

                                                                                                        Mechanism Of Action

                                                                                                          R&D Progress

                                                                                                            Recombinant Protein for RSV Infections - Drug Profile

                                                                                                              Product Description

                                                                                                                Mechanism Of Action

                                                                                                                  R&D Progress

                                                                                                                    sargramostim - Drug Profile

                                                                                                                      Product Description

                                                                                                                        Mechanism Of Action

                                                                                                                          R&D Progress

                                                                                                                            sargramostim - Drug Profile

                                                                                                                              Product Description

                                                                                                                                Mechanism Of Action

                                                                                                                                  R&D Progress

                                                                                                                                    Vaccine for Melanoma - Drug Profile

                                                                                                                                      Product Description

                                                                                                                                        Mechanism Of Action

                                                                                                                                          R&D Progress

                                                                                                                                            XL-150 - Drug Profile

                                                                                                                                              Product Description

                                                                                                                                                Mechanism Of Action

                                                                                                                                                  R&D Progress

                                                                                                                                                    Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Dormant Products

                                                                                                                                                      Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Discontinued Products

                                                                                                                                                        Granulocyte Macrophage Colony Stimulating Factor Receptor Subunit Alpha (CDw116 or CD116 or CSF2RA) - Product Development Milestones

                                                                                                                                                          Featured News & Press Releases

                                                                                                                                                            Jul 15, 2019: Targovax announces start of the expansion part in the phase I/II trial with ONCOS-102 in combination with durvalumab in patients with advanced peritoneal malignancies

                                                                                                                                                              Jul 08, 2019: Targovax announces encouraging results from part 1 of the ONCOS-102 and Keytruda combination trial in Anti-PD1 refractory melanoma

                                                                                                                                                                Jun 12, 2019: Savara Announces Results of IMPALA, a Phase 3 Study of Molgradex for the Treatment of Autoimmune Alveolar Pulmonary Proteinosis (aPAP)

                                                                                                                                                                  Jun 03, 2019: Targovax announces publication of in vivo abscopal effect of ONCOS-102 and Keytruda combination

                                                                                                                                                                    May 23, 2019: Targovax to fully focus on ONCOS Oncolytic virus program

                                                                                                                                                                      May 23, 2019: Targovax - approval and publication of supplemental prospectus

                                                                                                                                                                        May 08, 2019: Savara Pharmaceuticals: Investigating GM-CSF in aPAP - A logical replacement of a dysfunctional protein

                                                                                                                                                                          May 08, 2019: Targovax announces completed enrollment of ONCOS-102 trial in mesothelioma

                                                                                                                                                                            May 06, 2019: Savara announces Molgradex received Fast Track Designation by FDA for treatment of autoimmune pulmonary alveolar proteinosis

                                                                                                                                                                              Apr 01, 2019: Savara initiates phase 2a clinical study of Molgradex for the treatment of NTM lung infection in people living with cystic fibrosis

                                                                                                                                                                                Feb 11, 2019: First patient treated in dose expansion cohort of Targovax's ONCOS-102 trial in melanoma

                                                                                                                                                                                  Dec 12, 2018: Targovax presents at DNB 9th Annual Nordic Healthcare Conference

                                                                                                                                                                                    Nov 02, 2018: Savara completes enrolment for Phase IIa Molgradex trial

                                                                                                                                                                                      Oct 24, 2018: Bolder BioTechnology to present preclinical data of BBT-007 at Acute Radiation Syndrome Meeting

                                                                                                                                                                                        Oct 15, 2018: Savara completes enrollment in pivotal Molgradex impala clinical study for the treatment of aPAP

                                                                                                                                                                                          Appendix

                                                                                                                                                                                            Methodology

                                                                                                                                                                                              Coverage

                                                                                                                                                                                                Secondary Research

                                                                                                                                                                                                  Primary Research

                                                                                                                                                                                                    Expert Panel Validation

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