According to our (Global Info Research) latest study, the global Animal Free Medium market size was valued at US$ 848 million in 2025 and is forecast to a readjusted size of US$ 1367 million by 2032 with a CAGR of 6.8% during review period.
Global sales of animal-free medium reached 4,819 kiloliters in 2025, with an average price of US$171 per liter.
Animal component-free medium (ACFM or ADCF) refers to a product or its primary and secondary raw materials that do not use any components directly derived from animal (including human) tissues or body fluids; however, the use of plant, microbial, or recombinant (non-animal cell expression) proteins as functional substitutes is permitted.
The main raw materials are plant or microbial hydrolysates (soybean, wheat, yeast peptides, accounting for 12–15% of the cost), recombinant insulin/transferrin/albumin (yeast or E. coli expression, accounting for 20–25%), synthetic lipids and steroids (accounting for 8–10%), and trace elements, buffer salts, and other bulk chemicals (accounting for 15%). Because animal blood collection, serum grading, and virus inactivation are eliminated, upstream raw material prices are relatively stable. However, recombinant proteins still rely on high-density fermentation and multi-step purification; their production capacity and yield determine the overall cost. Domestic supply chains have already replaced over 60% of imports for rInsulin and rHSA, resulting in an average price reduction of approximately 15% in 2025 compared to 2022. The key bottleneck lies in the batch scale-up of recombinant transferrin and plant-derived hydrolysates, accounting for 30-35% of material costs and representing the next key area for cost reduction.
This report is a detailed and comprehensive analysis for global Animal Free Medium market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global Animal Free Medium market size and forecasts, in consumption value ($ Million), sales quantity (L), and average selling prices (US$/L), 2021-2032
Global Animal Free Medium market size and forecasts by region and country, in consumption value ($ Million), sales quantity (L), and average selling prices (US$/L), 2021-2032
Global Animal Free Medium market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (L), and average selling prices (US$/L), 2021-2032
Global Animal Free Medium market shares of main players, shipments in revenue ($ Million), sales quantity (L), and ASP (US$/L), 2021-2026
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for Animal Free Medium
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global Animal Free Medium market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Thermo Fisher, Merck KGaA, Corning, Cytiva, Lonza, FUJIFILM Irvine Scientific, HiMedia Labs, Takara, R&D Systems, Zenbio, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market Segmentation
Animal Free Medium market is split by Type and by Application. For the period 2021-2032, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Type
High Protein
Low Protein
No Protein
Market segment by Raw Materials
Plant Derivative
Microbial Fermentation
Recombinant
Market segment by Cell Direction
CHO-ACF
HEK-ACF
MSC-ACF
T-ACF
Market segment by Application
Antibody/Recombinant Protein
Vaccines and Viral Vectors
Cell/Gene Therapy
Cultivated Meat and Tissue Engineering
Other
Major players covered
Thermo Fisher
Merck KGaA
Corning
Cytiva
Lonza
FUJIFILM Irvine Scientific
HiMedia Labs
Takara
R&D Systems
Zenbio
Jianshun Biosicences
OPM Biosciences
Yocon
Minhai Bio
BIOENGINE
Market segment by region, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe Animal Free Medium product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of Animal Free Medium, with price, sales quantity, revenue, and global market share of Animal Free Medium from 2021 to 2026.
Chapter 3, the Animal Free Medium competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the Animal Free Medium breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2021 to 2032.
Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2021 to 2032.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2021 to 2026.and Animal Free Medium market forecast, by regions, by Type, and by Application, with sales and revenue, from 2027 to 2032.
Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
Chapter 13, the key raw materials and key suppliers, and industry chain of Animal Free Medium.
Chapter 14 and 15, to describe Animal Free Medium sales channel, distributors, customers, research findings and conclusion.
Summary:
Get latest Market Research Reports on Animal Free Medium. Industry analysis & Market Report on Animal Free Medium is a syndicated market report, published as Global Animal Free Medium Market 2026 by Manufacturers, Regions, Type and Application, Forecast to 2032. It is complete Research Study and Industry Analysis of Animal Free Medium market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.