According to our (Global Info Research) latest study, the global Technetium-99m market size was valued at US$ 577 million in 2025 and is forecast to a readjusted size of US$ 799 million by 2032 with a CAGR of 4.5% during review period.
Technetium-99m is a nuclear isomer of technetium-99 and the most widely used radiopharmaceutical in diagnostic nuclear medicine. The "m" stands for metastable, indicating that the nucleus remains in an excited state for a measurable period before decaying. It is typically generated from the decay of Molybdenum-99 in a technetium generator. With a physical half-life of approximately 6.02 hours, Tc99 decays by emitting a gamma photon with a principal energy of 140 keV, which is ideal for detection by gamma cameras and Single-Photon Emission Computed Tomography (SPECT). Its optimal energy profile, short half-life (which minimizes patient radiation exposure), and versatile chemistry for labeling various biological compounds make it the "gold standard" for imaging the skeleton, heart, and various internal organs.In 2025, global Technetium-99m production reached approximately 546.98 K Curie.
Technetium-99m (Tc-99m) is the most widely used and strategically important radionuclide in the global nuclear medicine diagnostics market, often regarded as the cornerstone of modern medical imaging. Owing to its favorable physical characteristics—such as a short half-life of approximately six hours, an optimal gamma emission energy of 140 keV, and relatively low radiation exposure to patients—Tc-99m is extensively used in single-photon emission computed tomography (SPECT). It plays a dominant role in diagnostic imaging for cardiology, orthopedics, oncology, nephrology, pulmonology, and thyroid disorders. Globally, Tc-99m-based procedures consistently account for more than 70% of all nuclear medicine diagnostic examinations, underscoring its entrenched and resilient market position.
From a supply perspective, Technetium-99m is not produced directly but is obtained through the radioactive decay of its parent isotope, Molybdenum-99 (Mo-99), and distributed primarily via Tc-99m generators. This supply structure results in a highly centralized and sensitive upstream market. Historically, global Mo-99 production has relied on a limited number of aging research reactors, making the Tc-99m supply chain vulnerable to maintenance shutdowns, operational disruptions, and geopolitical risks. As a result, supply security has become a critical issue for healthcare systems worldwide, driving investment into alternative production methods, including low-enriched uranium (LEU)-based reactors, accelerator-based technologies, and regionalized isotope manufacturing initiatives.
On the demand side, the market for Tc-99m is closely linked to demographic and epidemiological trends, particularly population aging and the rising prevalence of chronic diseases. Cardiovascular diseases, bone disorders, and cancer screening increasingly rely on nuclear imaging for early detection and functional assessment, reinforcing Tc-99m’s role as a “workhorse” isotope in routine diagnostics. In emerging economies and developing regions, SPECT systems combined with Tc-99m radiopharmaceuticals offer a cost-effective and scalable solution compared to PET imaging, which requires higher capital investment and more complex infrastructure. This dynamic supports sustained demand growth for Tc-99m in markets with expanding healthcare access.
In terms of competition and substitution, positron emission tomography (PET) and radionuclides such as Fluorine-18 are experiencing rapid growth in high-end diagnostic applications. However, their higher costs, logistical challenges, and limited accessibility constrain their ability to fully replace Tc-99m in mainstream clinical practice. Instead, Tc-99m continues to evolve through the development of new radiopharmaceutical kits, improved targeting specificity, and enhanced imaging protocols. Regulatory pathways for Tc-99m-based products are also well established in most major markets, facilitating ongoing innovation and clinical adoption.
Looking ahead, the Technetium-99m market is expected to demonstrate structural stability with gradual supply-side optimization and technological diversification. While demand fundamentals remain strong due to the essential role of nuclear medicine diagnostics, advancements in Mo-99 production and isotope supply resilience will reduce systemic risks over time. Ultimately, Tc-99m is not merely a diagnostic isotope but a critical infrastructure component of global healthcare systems, with enduring strategic and economic significance in the nuclear medicine value chain.
This report is a detailed and comprehensive analysis for global Technetium-99m market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global Technetium-99m market size and forecasts, in consumption value ($ Million), sales quantity (Curie), and average selling prices (US$/Curie), 2021-2032
Global Technetium-99m market size and forecasts by region and country, in consumption value ($ Million), sales quantity (Curie), and average selling prices (US$/Curie), 2021-2032
Global Technetium-99m market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (Curie), and average selling prices (US$/Curie), 2021-2032
Global Technetium-99m market shares of main players, shipments in revenue ($ Million), sales quantity (Curie), and ASP (US$/Curie), 2021-2026
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for Technetium-99m
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global Technetium-99m market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include NRG, Rosatom, ANSTO, Nordion, IRE, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market Segmentation
Technetium-99m market is split by Type and by Application. For the period 2021-2032, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Type
Produced by HEU
Produced by LEU
Market segment by Production Method
Generator-Derived
Cyclotron-Produced
Market segment by Clinical Procedure
Planar Imaging
SPECT
Market segment by Application
Medical Imaging
Others
Major players covered
NRG
Rosatom
ANSTO
Nordion
IRE
Market segment by region, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe Technetium-99m product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of Technetium-99m, with price, sales quantity, revenue, and global market share of Technetium-99m from 2021 to 2026.
Chapter 3, the Technetium-99m competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the Technetium-99m breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2021 to 2032.
Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2021 to 2032.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2021 to 2026.and Technetium-99m market forecast, by regions, by Type, and by Application, with sales and revenue, from 2027 to 2032.
Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
Chapter 13, the key raw materials and key suppliers, and industry chain of Technetium-99m.
Chapter 14 and 15, to describe Technetium-99m sales channel, distributors, customers, research findings and conclusion.
Summary:
Get latest Market Research Reports on Technetium-99m. Industry analysis & Market Report on Technetium-99m is a syndicated market report, published as Global Technetium-99m Market 2026 by Manufacturers, Regions, Type and Application, Forecast to 2032. It is complete Research Study and Industry Analysis of Technetium-99m market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.