According to our (Global Info Research) latest study, the global Polydeoxyribonudeotide (PDRN) market size was valued at US$ 103 million in 2025 and is forecast to a readjusted size of US$ 694 million by 2032 with a CAGR of 31.7% during review period.
PDRN is deoxyribonucleic acid(DNA) product, mainly comes from semen and roe of fish, rapidly repair injured scars. It can promote the collagen synthesis on the cell surface, reverse aging signs. PDRN is the excellent skin repair product widely used for both high-end beauty products and medical products. Strong functions of anti-radiation and shrinking pores, make skin appears brightly and elastically.
Polydeoxyribonucleotide (PDRN) and polynucleotide (PN) are regenerative materials extracted from the regenerative cell (sperm and testicle) gene segment (DNA) of salmon or trout. The molecular sizes of PDRN and PN are different (PN is bigger) and they are safe biogenic substances approved by the Ministry of Food and Drug Safety. PDRN are often used in pharmaceuticals for tissue regeneration and cornea regeneration as well as treatment and tissue restoration of wounds. PN is often used for medical devices (tissue regeneration) for skin regeneration, articular cartilage regeneration, and osteogenic tissues.
Both PDRN and PN are included in the report.
As a product of regenerative medicine, PDRN can synthesize DNA from damaged or hypoxic tissues, activate the regeneration of endogenous growth factors such as FGF, IGF, and EGF, accelerate cell metabolism, and improve skin repair and regeneration capabilities. The fiber network full of collagen and elastin can achieve skin rejuvenation, improve skin microenvironment, increase skin thickness, etc., so as to achieve the effect of improving problem skin.
The PDRN market has shown a significant growth trend in recent years, mainly driven by the field of regenerative medicine and tissue engineering, as well as the field of aesthetics. Demand for innovative solutions in medical fields such as wound healing, dermatology, orthopedics is driving the demand for PDRN products and therapies.
In terms of product types, freeze-dried powder occupies an important position, dominated with 65% market share in 2024, preferred for stability and versatility in pharmaceuticals and cosmetics. While PDRN Solutions are growing demand in injectables (e.g., mesotherapy), especially in Korea’s "salmon needle" treatments. Expected to surge due to ease of clinical applicationAt the same time, in terms of application, the share of Medical Aesthetics (Mesotherapy) in 2024 is about 32%, used in "regenerative hydrogels" for collagen synthesis and anti-inflammatory effects.
The major global manufacturers of Polydeoxyribonudeotide (PDRN) include HTL Biotechnology, Ruijiming Biological, PharmaResearch Co., Ltd., Humedix, ReaLi Tide Biological, HENGYU BIOPH, Mastelli, Dongkook, BR PHARM, BMI KOREA, BNF Solution, etc. In 2024, the world's top three vendors accounted for approximately 56% of the revenue.
As a new type of regenerative material, PDRN has multiple activities such as promoting skin damage repair, anti-inflammatory, promoting angiogenesis, improving tissue microcirculation, etc. It has broad application prospects in the fields of medical devices, medicine, cosmetics, health foods, daily chemical products, medical cosmetology, etc. In the future, with the rise of medical beauty consumption and the expansion of application fields, the scale of the PDRN market will further expand. The PDRN market is poised for explosive growth, anchored by Asia-Pacific’s dominance (Korea/China) and diversification into cosmetics/wound care. Key developments include China’s regulatory openings, plant-based innovations, and the rise of "regenerative aesthetics."
This report is a detailed and comprehensive analysis for global Polydeoxyribonudeotide (PDRN) market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global Polydeoxyribonudeotide (PDRN) market size and forecasts, in consumption value ($ Million), sales quantity (Kg), and average selling prices (US$/g), 2021-2032
Global Polydeoxyribonudeotide (PDRN) market size and forecasts by region and country, in consumption value ($ Million), sales quantity (Kg), and average selling prices (US$/g), 2021-2032
Global Polydeoxyribonudeotide (PDRN) market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (Kg), and average selling prices (US$/g), 2021-2032
Global Polydeoxyribonudeotide (PDRN) market shares of main players, shipments in revenue ($ Million), sales quantity (Kg), and ASP (US$/g), 2021-2026
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for Polydeoxyribonudeotide (PDRN)
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global Polydeoxyribonudeotide (PDRN) market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include HTL Biotechnology, ReaLi Tide Biological, PharmaResearch Co., Ltd., Humedix, Ruijiming Biological, Bloomage Biotech, HENGYU BIOPH, Mastelli, Dongkook, BR PHARM, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market Segmentation
Polydeoxyribonudeotide (PDRN) market is split by Type and by Application. For the period 2021-2032, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Type
Powder
Solution
Market segment by Application
Mesotherapy
Bone Injection & Dermal Fillers
Pharmaceutical
Cosmetic
Wound Healing Products and Others
Major players covered
HTL Biotechnology
ReaLi Tide Biological
PharmaResearch Co., Ltd.
Humedix
Ruijiming Biological
Bloomage Biotech
HENGYU BIOPH
Mastelli
Dongkook
BR PHARM
BNC Global
BMI KOREA
BNF Solution
Nanjing Letop Biotechnology
Topscience Biotech
Freda Biotechnology
Shebah Biotech
APR Corporation
Kolmar Korea
PORIBIO INC.
Market segment by region, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe Polydeoxyribonudeotide (PDRN) product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of Polydeoxyribonudeotide (PDRN), with price, sales quantity, revenue, and global market share of Polydeoxyribonudeotide (PDRN) from 2021 to 2026.
Chapter 3, the Polydeoxyribonudeotide (PDRN) competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the Polydeoxyribonudeotide (PDRN) breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2021 to 2032.
Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2021 to 2032.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2021 to 2026.and Polydeoxyribonudeotide (PDRN) market forecast, by regions, by Type, and by Application, with sales and revenue, from 2027 to 2032.
Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
Chapter 13, the key raw materials and key suppliers, and industry chain of Polydeoxyribonudeotide (PDRN).
Chapter 14 and 15, to describe Polydeoxyribonudeotide (PDRN) sales channel, distributors, customers, research findings and conclusion.
Summary:
Get latest Market Research Reports on Polydeoxyribonudeotide (PDRN). Industry analysis & Market Report on Polydeoxyribonudeotide (PDRN) is a syndicated market report, published as Global Polydeoxyribonudeotide (PDRN) Market 2026 by Manufacturers, Regions, Type and Application, Forecast to 2032. It is complete Research Study and Industry Analysis of Polydeoxyribonudeotide (PDRN) market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.