According to our (Global Info Research) latest study, the global Oxygen-18 Water market size was valued at US$ 148 million in 2025 and is forecast to a readjusted size of US$ 210 million by 2032 with a CAGR of 5.1% during review period.
Oxygen-18 Water is a stable isotope-labeled water in which the oxygen component is enriched with the stable isotope oxygen-18. It is commonly expressed as H₂¹⁸O, Water-¹⁸O or O-18 Water. Compared with ordinary water, its basic chemical behavior is similar, but the enriched oxygen isotope gives it high value as a nuclear target material, isotope tracer and analytical reagent. In the radiopharmaceutical industry, high-enrichment Oxygen-18 Water is mainly used as the liquid target material in cyclotrons to generate fluorine-18, which is then used to synthesize fluorine-18 labeled PET radiopharmaceuticals such as ¹⁸F-FDG.
The upstream raw materials and inputs of Oxygen-18 Water mainly include natural water or oxygen-containing feedstocks with natural oxygen isotope composition, high-purity water, oxygen or hydrogen related feed gases and utilities, isotope-enriched oxygen intermediates, purification consumables and high-cleanliness packaging materials. For PET and radiopharmaceutical applications, the product usually requires high oxygen-18 enrichment, low organic carbon, low ionic impurity, controlled conductivity and clean vial or bottle packaging. The downstream market is concentrated in PET radiopharmaceutical manufacturers, cyclotron centers, nuclear medicine departments, isotope research laboratories, pharmaceutical research institutions, life science laboratories and environmental isotope analysis institutions.
In 2025, global sales of Oxygen-18 Water reached approximately 2,051 kg, with an average global market price of around US$ 70/g. As a niche chemical, its global production capacity is low, and its gross profit margin is approximately 50%-80%.
This report is a detailed and comprehensive analysis for global Oxygen-18 Water market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global Oxygen-18 Water market size and forecasts, in consumption value ($ Million), sales quantity (kg), and average selling prices (US$/g), 2021-2032
Global Oxygen-18 Water market size and forecasts by region and country, in consumption value ($ Million), sales quantity (kg), and average selling prices (US$/g), 2021-2032
Global Oxygen-18 Water market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (kg), and average selling prices (US$/g), 2021-2032
Global Oxygen-18 Water market shares of main players, shipments in revenue ($ Million), sales quantity (kg), and ASP (US$/g), 2021-2026
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for Oxygen-18 Water
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global Oxygen-18 Water market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Nippon Sanso, Rotem Industries, Cambridge Isotope Laboratories, Marshall Isotopes, Center of Molecular Research (CMR), Heavy Water Board, Mesbah Energy, QuTope, Wo Isotope, Jiangsu Huayi Technology, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market Segmentation
Oxygen-18 Water market is split by Type and by Application. For the period 2021-2032, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Type
Ultra-high Enrichment Grade (>98%)
High Enrichment Grade (95%-98%)
Low-to-Medium Enrichment Grade (<95%)
Market segment by Grade
PET Target Grade
Analytical Research Grade
Industrial Isotope Grade
Market segment by Isotopic Composition Form
单标记氧18水
双标水配方
其他
Market segment by Application
PET Radiopharmaceutical Production
Life Science and Metabolic Research
Environmental Hydrological Analysis
Other
Major players covered
Nippon Sanso
Rotem Industries
Cambridge Isotope Laboratories
Marshall Isotopes
Center of Molecular Research (CMR)
Heavy Water Board
Mesbah Energy
QuTope
Wo Isotope
Jiangsu Huayi Technology
Shanghai Research Institute of Chemical Industry
Market segment by region, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe Oxygen-18 Water product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of Oxygen-18 Water, with price, sales quantity, revenue, and global market share of Oxygen-18 Water from 2021 to 2026.
Chapter 3, the Oxygen-18 Water competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the Oxygen-18 Water breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2021 to 2032.
Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2021 to 2032.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2021 to 2026.and Oxygen-18 Water market forecast, by regions, by Type, and by Application, with sales and revenue, from 2027 to 2032.
Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
Chapter 13, the key raw materials and key suppliers, and industry chain of Oxygen-18 Water.
Chapter 14 and 15, to describe Oxygen-18 Water sales channel, distributors, customers, research findings and conclusion.
Summary:
Get latest Market Research Reports on Oxygen-18 Water. Industry analysis & Market Report on Oxygen-18 Water is a syndicated market report, published as Global Oxygen-18 Water Market 2026 by Manufacturers, Regions, Type and Application, Forecast to 2032. It is complete Research Study and Industry Analysis of Oxygen-18 Water market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.