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Pharma & Healthcare Global Oligonucleotide Therapeutics Market 2026 by Company, Regions, Type and Application, Forecast to 2032

  • RnM4669007
    • |
  • 22 January, 2026
    • |
  • Global
    • |
  • 135 Pages
    • |
  • GIR
    • |
  • Pharma & Healthcare

According to our (Global Info Research) latest study, the global Oligonucleotide Therapeutics market size was valued at US$ 8013 million in 2025 and is forecast to a readjusted size of US$ 10250 million by 2032 with a CAGR of 3.6% during review period.
Oligonucleotide therapeutics are a class of precision medicines composed of short DNA or RNA sequences designed to specifically target and modulate the expression of genes involved in disease processes. These therapies can act by silencing, inhibiting, or correcting genetic abnormalities at the molecular level, offering a highly targeted approach to treat various conditions such as genetic disorders, cancers, and viral infections. Oligonucleotide therapeutics include antisense oligonucleotides, small interfering RNA (siRNA), and aptamers, and they represent a promising area of drug development due to their ability to address previously untreatable diseases.
Key driver of the oligonucleotide therapeutics market is the growing prevalence of genetic and rare diseases that require precise and targeted treatment options. Advances in genomics and personalized medicine have fueled interest in oligonucleotide therapies, which can directly modulate gene expression and offer solutions for conditions that were previously difficult to treat. The success of approved oligonucleotide drugs, such as antisense oligonucleotides and siRNA therapies, has increased confidence in this field, leading to more investments and research in developing novel treatments for a wide range of diseases, including cancers and neurological disorders.
One significant challenge in the oligonucleotide therapeutics market is the complexity of delivering these molecules effectively to target cells or tissues. Oligonucleotides are large, negatively charged molecules that face hurdles in stability, bioavailability, and efficient cellular uptake. Developing delivery systems that can ensure targeted and sustained delivery while minimizing immune responses or off-target effects remains a critical challenge. Additionally, the high costs associated with research, development, and manufacturing of oligonucleotide-based drugs pose financial challenges, limiting accessibility and widespread adoption, especially in resource-constrained healthcare settings.
Europe is the largest consumption place, with a consumption market share nearly 44.61% in 2023. Following Europe, North Americas is the second largest consumption place with the consumption market share of 34.9%. The global key companies of oligonucleotide therapeutics include Pfizer, Moderna Therapeutics, BioNTech, Biogen, Alnylam, Sarepta Therapeutics, Jazz Pharmaceuticals, Nippon Shinyaku, Novartis, Sobi, Ionis Pharmaceuticals, etc. In 2023, the global top five players had a share approximately 97.87% in terms of revenue.
This report is a detailed and comprehensive analysis for global Oligonucleotide Therapeutics market. Both quantitative and qualitative analyses are presented by company, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global Oligonucleotide Therapeutics market size and forecasts, in consumption value ($ Million), 2021-2032
Global Oligonucleotide Therapeutics market size and forecasts by region and country, in consumption value ($ Million), 2021-2032
Global Oligonucleotide Therapeutics market size and forecasts, by Type and by Application, in consumption value ($ Million), 2021-2032
Global Oligonucleotide Therapeutics market shares of main players, in revenue ($ Million), 2021-2026
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for Oligonucleotide Therapeutics
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global Oligonucleotide Therapeutics market based on the following parameters - company overview, revenue, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Sarepta Therapeutics, Ionis Pharmaceuticals, Alnylam, Biogen, Nippon Shinyaku, Sobi, Novartis, BioNTech, Pfizer, Moderna Therapeutics, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market segmentation
Oligonucleotide Therapeutics market is split by Type and by Application. For the period 2021-2032, the growth among segments provides accurate calculations and forecasts for Consumption Value by Type and by Application. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Type
Antisense Oligonucleotides (ASO)
siRNA
mRNA
Market segment by Application
Neuromuscular Diseases
hATTR
COVID-19
Other
Market segment by players, this report covers
Sarepta Therapeutics
Ionis Pharmaceuticals
Alnylam
Biogen
Nippon Shinyaku
Sobi
Novartis
BioNTech
Pfizer
Moderna Therapeutics
Jazz Pharmaceuticals
CureVac
Regulus Therapeutics
ProQR
Secarna
MiNA Therapeutics
Sylentis
Arrowhead
Silence Therapeutics
Dicerna
Market segment by regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia, Italy and Rest of Europe)
Asia-Pacific (China, Japan, South Korea, India, Southeast Asia and Rest of Asia-Pacific)
South America (Brazil, Rest of South America)
Middle East & Africa (Turkey, Saudi Arabia, UAE, Rest of Middle East & Africa)
The content of the study subjects, includes a total of 13 chapters:
Chapter 1, to describe Oligonucleotide Therapeutics product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top players of Oligonucleotide Therapeutics, with revenue, gross margin, and global market share of Oligonucleotide Therapeutics from 2021 to 2026.
Chapter 3, the Oligonucleotide Therapeutics competitive situation, revenue, and global market share of top players are analyzed emphatically by landscape contrast.
Chapter 4 and 5, to segment the market size by Type and by Application, with consumption value and growth rate by Type, by Application, from 2021 to 2032.
Chapter 6, 7, 8, 9, and 10, to break the market size data at the country level, with revenue and market share for key countries in the world, from 2021 to 2026.and Oligonucleotide Therapeutics market forecast, by regions, by Type and by Application, with consumption value, from 2027 to 2032.
Chapter 11, market dynamics, drivers, restraints, trends, Porters Five Forces analysis.
Chapter 12, the key raw materials and key suppliers, and industry chain of Oligonucleotide Therapeutics.
Chapter 13, to describe Oligonucleotide Therapeutics research findings and conclusion.


1 Market Overview

  • 1.1 Product Overview and Scope
  • 1.2 Market Estimation Caveats and Base Year
  • 1.3 Classification of Oligonucleotide Therapeutics by Type
    • 1.3.1 Overview: Global Oligonucleotide Therapeutics Market Size by Type: 2021 Versus 2025 Versus 2032
    • 1.3.2 Global Oligonucleotide Therapeutics Consumption Value Market Share by Type in 2025
    • 1.3.3 Antisense Oligonucleotides (ASO)
    • 1.3.4 siRNA
    • 1.3.5 mRNA
  • 1.4 Global Oligonucleotide Therapeutics Market by Application
    • 1.4.1 Overview: Global Oligonucleotide Therapeutics Market Size by Application: 2021 Versus 2025 Versus 2032
    • 1.4.2 Neuromuscular Diseases
    • 1.4.3 hATTR
    • 1.4.4 COVID-19
    • 1.4.5 Other
  • 1.5 Global Oligonucleotide Therapeutics Market Size & Forecast
  • 1.6 Global Oligonucleotide Therapeutics Market Size and Forecast by Region
    • 1.6.1 Global Oligonucleotide Therapeutics Market Size by Region: 2021 VS 2025 VS 2032
    • 1.6.2 Global Oligonucleotide Therapeutics Market Size by Region, (2021-2032)
    • 1.6.3 North America Oligonucleotide Therapeutics Market Size and Prospect (2021-2032)
    • 1.6.4 Europe Oligonucleotide Therapeutics Market Size and Prospect (2021-2032)
    • 1.6.5 Asia-Pacific Oligonucleotide Therapeutics Market Size and Prospect (2021-2032)
    • 1.6.6 South America Oligonucleotide Therapeutics Market Size and Prospect (2021-2032)
    • 1.6.7 Middle East & Africa Oligonucleotide Therapeutics Market Size and Prospect (2021-2032)

2 Company Profiles

  • 2.1 Sarepta Therapeutics
    • 2.1.1 Sarepta Therapeutics Details
    • 2.1.2 Sarepta Therapeutics Major Business
    • 2.1.3 Sarepta Therapeutics Oligonucleotide Therapeutics Product and Solutions
    • 2.1.4 Sarepta Therapeutics Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.1.5 Sarepta Therapeutics Recent Developments and Future Plans
  • 2.2 Ionis Pharmaceuticals
    • 2.2.1 Ionis Pharmaceuticals Details
    • 2.2.2 Ionis Pharmaceuticals Major Business
    • 2.2.3 Ionis Pharmaceuticals Oligonucleotide Therapeutics Product and Solutions
    • 2.2.4 Ionis Pharmaceuticals Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.2.5 Ionis Pharmaceuticals Recent Developments and Future Plans
  • 2.3 Alnylam
    • 2.3.1 Alnylam Details
    • 2.3.2 Alnylam Major Business
    • 2.3.3 Alnylam Oligonucleotide Therapeutics Product and Solutions
    • 2.3.4 Alnylam Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.3.5 Alnylam Recent Developments and Future Plans
  • 2.4 Biogen
    • 2.4.1 Biogen Details
    • 2.4.2 Biogen Major Business
    • 2.4.3 Biogen Oligonucleotide Therapeutics Product and Solutions
    • 2.4.4 Biogen Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.4.5 Biogen Recent Developments and Future Plans
  • 2.5 Nippon Shinyaku
    • 2.5.1 Nippon Shinyaku Details
    • 2.5.2 Nippon Shinyaku Major Business
    • 2.5.3 Nippon Shinyaku Oligonucleotide Therapeutics Product and Solutions
    • 2.5.4 Nippon Shinyaku Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.5.5 Nippon Shinyaku Recent Developments and Future Plans
  • 2.6 Sobi
    • 2.6.1 Sobi Details
    • 2.6.2 Sobi Major Business
    • 2.6.3 Sobi Oligonucleotide Therapeutics Product and Solutions
    • 2.6.4 Sobi Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.6.5 Sobi Recent Developments and Future Plans
  • 2.7 Novartis
    • 2.7.1 Novartis Details
    • 2.7.2 Novartis Major Business
    • 2.7.3 Novartis Oligonucleotide Therapeutics Product and Solutions
    • 2.7.4 Novartis Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.7.5 Novartis Recent Developments and Future Plans
  • 2.8 BioNTech
    • 2.8.1 BioNTech Details
    • 2.8.2 BioNTech Major Business
    • 2.8.3 BioNTech Oligonucleotide Therapeutics Product and Solutions
    • 2.8.4 BioNTech Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.8.5 BioNTech Recent Developments and Future Plans
  • 2.9 Pfizer
    • 2.9.1 Pfizer Details
    • 2.9.2 Pfizer Major Business
    • 2.9.3 Pfizer Oligonucleotide Therapeutics Product and Solutions
    • 2.9.4 Pfizer Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.9.5 Pfizer Recent Developments and Future Plans
  • 2.10 Moderna Therapeutics
    • 2.10.1 Moderna Therapeutics Details
    • 2.10.2 Moderna Therapeutics Major Business
    • 2.10.3 Moderna Therapeutics Oligonucleotide Therapeutics Product and Solutions
    • 2.10.4 Moderna Therapeutics Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.10.5 Moderna Therapeutics Recent Developments and Future Plans
  • 2.11 Jazz Pharmaceuticals
    • 2.11.1 Jazz Pharmaceuticals Details
    • 2.11.2 Jazz Pharmaceuticals Major Business
    • 2.11.3 Jazz Pharmaceuticals Oligonucleotide Therapeutics Product and Solutions
    • 2.11.4 Jazz Pharmaceuticals Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.11.5 Jazz Pharmaceuticals Recent Developments and Future Plans
  • 2.12 CureVac
    • 2.12.1 CureVac Details
    • 2.12.2 CureVac Major Business
    • 2.12.3 CureVac Oligonucleotide Therapeutics Product and Solutions
    • 2.12.4 CureVac Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.12.5 CureVac Recent Developments and Future Plans
  • 2.13 Regulus Therapeutics
    • 2.13.1 Regulus Therapeutics Details
    • 2.13.2 Regulus Therapeutics Major Business
    • 2.13.3 Regulus Therapeutics Oligonucleotide Therapeutics Product and Solutions
    • 2.13.4 Regulus Therapeutics Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.13.5 Regulus Therapeutics Recent Developments and Future Plans
  • 2.14 ProQR
    • 2.14.1 ProQR Details
    • 2.14.2 ProQR Major Business
    • 2.14.3 ProQR Oligonucleotide Therapeutics Product and Solutions
    • 2.14.4 ProQR Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.14.5 ProQR Recent Developments and Future Plans
  • 2.15 Secarna
    • 2.15.1 Secarna Details
    • 2.15.2 Secarna Major Business
    • 2.15.3 Secarna Oligonucleotide Therapeutics Product and Solutions
    • 2.15.4 Secarna Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.15.5 Secarna Recent Developments and Future Plans
  • 2.16 MiNA Therapeutics
    • 2.16.1 MiNA Therapeutics Details
    • 2.16.2 MiNA Therapeutics Major Business
    • 2.16.3 MiNA Therapeutics Oligonucleotide Therapeutics Product and Solutions
    • 2.16.4 MiNA Therapeutics Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.16.5 MiNA Therapeutics Recent Developments and Future Plans
  • 2.17 Sylentis
    • 2.17.1 Sylentis Details
    • 2.17.2 Sylentis Major Business
    • 2.17.3 Sylentis Oligonucleotide Therapeutics Product and Solutions
    • 2.17.4 Sylentis Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.17.5 Sylentis Recent Developments and Future Plans
  • 2.18 Arrowhead
    • 2.18.1 Arrowhead Details
    • 2.18.2 Arrowhead Major Business
    • 2.18.3 Arrowhead Oligonucleotide Therapeutics Product and Solutions
    • 2.18.4 Arrowhead Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.18.5 Arrowhead Recent Developments and Future Plans
  • 2.19 Silence Therapeutics
    • 2.19.1 Silence Therapeutics Details
    • 2.19.2 Silence Therapeutics Major Business
    • 2.19.3 Silence Therapeutics Oligonucleotide Therapeutics Product and Solutions
    • 2.19.4 Silence Therapeutics Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.19.5 Silence Therapeutics Recent Developments and Future Plans
  • 2.20 Dicerna
    • 2.20.1 Dicerna Details
    • 2.20.2 Dicerna Major Business
    • 2.20.3 Dicerna Oligonucleotide Therapeutics Product and Solutions
    • 2.20.4 Dicerna Oligonucleotide Therapeutics Revenue, Gross Margin and Market Share (2021-2026)
    • 2.20.5 Dicerna Recent Developments and Future Plans

3 Market Competition, by Players

  • 3.1 Global Oligonucleotide Therapeutics Revenue and Share by Players (2021-2026)
  • 3.2 Market Share Analysis (2025)
    • 3.2.1 Market Share of Oligonucleotide Therapeutics by Company Revenue
    • 3.2.2 Top 3 Oligonucleotide Therapeutics Players Market Share in 2025
    • 3.2.3 Top 6 Oligonucleotide Therapeutics Players Market Share in 2025
  • 3.3 Oligonucleotide Therapeutics Market: Overall Company Footprint Analysis
    • 3.3.1 Oligonucleotide Therapeutics Market: Region Footprint
    • 3.3.2 Oligonucleotide Therapeutics Market: Company Product Type Footprint
    • 3.3.3 Oligonucleotide Therapeutics Market: Company Product Application Footprint
  • 3.4 New Market Entrants and Barriers to Market Entry
  • 3.5 Mergers, Acquisition, Agreements, and Collaborations

4 Market Size Segment by Type

  • 4.1 Global Oligonucleotide Therapeutics Consumption Value and Market Share by Type (2021-2026)
  • 4.2 Global Oligonucleotide Therapeutics Market Forecast by Type (2027-2032)

5 Market Size Segment by Application

  • 5.1 Global Oligonucleotide Therapeutics Consumption Value Market Share by Application (2021-2026)
  • 5.2 Global Oligonucleotide Therapeutics Market Forecast by Application (2027-2032)

6 North America

  • 6.1 North America Oligonucleotide Therapeutics Consumption Value by Type (2021-2032)
  • 6.2 North America Oligonucleotide Therapeutics Market Size by Application (2021-2032)
  • 6.3 North America Oligonucleotide Therapeutics Market Size by Country
    • 6.3.1 North America Oligonucleotide Therapeutics Consumption Value by Country (2021-2032)
    • 6.3.2 United States Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 6.3.3 Canada Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 6.3.4 Mexico Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)

7 Europe

  • 7.1 Europe Oligonucleotide Therapeutics Consumption Value by Type (2021-2032)
  • 7.2 Europe Oligonucleotide Therapeutics Consumption Value by Application (2021-2032)
  • 7.3 Europe Oligonucleotide Therapeutics Market Size by Country
    • 7.3.1 Europe Oligonucleotide Therapeutics Consumption Value by Country (2021-2032)
    • 7.3.2 Germany Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 7.3.3 France Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 7.3.4 United Kingdom Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 7.3.5 Russia Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 7.3.6 Italy Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)

8 Asia-Pacific

  • 8.1 Asia-Pacific Oligonucleotide Therapeutics Consumption Value by Type (2021-2032)
  • 8.2 Asia-Pacific Oligonucleotide Therapeutics Consumption Value by Application (2021-2032)
  • 8.3 Asia-Pacific Oligonucleotide Therapeutics Market Size by Region
    • 8.3.1 Asia-Pacific Oligonucleotide Therapeutics Consumption Value by Region (2021-2032)
    • 8.3.2 China Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 8.3.3 Japan Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 8.3.4 South Korea Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 8.3.5 India Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 8.3.6 Southeast Asia Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 8.3.7 Australia Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)

9 South America

  • 9.1 South America Oligonucleotide Therapeutics Consumption Value by Type (2021-2032)
  • 9.2 South America Oligonucleotide Therapeutics Consumption Value by Application (2021-2032)
  • 9.3 South America Oligonucleotide Therapeutics Market Size by Country
    • 9.3.1 South America Oligonucleotide Therapeutics Consumption Value by Country (2021-2032)
    • 9.3.2 Brazil Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 9.3.3 Argentina Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)

10 Middle East & Africa

  • 10.1 Middle East & Africa Oligonucleotide Therapeutics Consumption Value by Type (2021-2032)
  • 10.2 Middle East & Africa Oligonucleotide Therapeutics Consumption Value by Application (2021-2032)
  • 10.3 Middle East & Africa Oligonucleotide Therapeutics Market Size by Country
    • 10.3.1 Middle East & Africa Oligonucleotide Therapeutics Consumption Value by Country (2021-2032)
    • 10.3.2 Turkey Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 10.3.3 Saudi Arabia Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)
    • 10.3.4 UAE Oligonucleotide Therapeutics Market Size and Forecast (2021-2032)

11 Market Dynamics

  • 11.1 Oligonucleotide Therapeutics Market Drivers
  • 11.2 Oligonucleotide Therapeutics Market Restraints
  • 11.3 Oligonucleotide Therapeutics Trends Analysis
  • 11.4 Porters Five Forces Analysis
    • 11.4.1 Threat of New Entrants
    • 11.4.2 Bargaining Power of Suppliers
    • 11.4.3 Bargaining Power of Buyers
    • 11.4.4 Threat of Substitutes
    • 11.4.5 Competitive Rivalry

12 Industry Chain Analysis

  • 12.1 Oligonucleotide Therapeutics Industry Chain
  • 12.2 Oligonucleotide Therapeutics Upstream Analysis
  • 12.3 Oligonucleotide Therapeutics Midstream Analysis
  • 12.4 Oligonucleotide Therapeutics Downstream Analysis

13 Research Findings and Conclusion

    14 Appendix

    • 14.1 Methodology
    • 14.2 Research Process and Data Source

    Summary:
    Get latest Market Research Reports on Oligonucleotide Therapeutics. Industry analysis & Market Report on Oligonucleotide Therapeutics is a syndicated market report, published as Global Oligonucleotide Therapeutics Market 2026 by Company, Regions, Type and Application, Forecast to 2032. It is complete Research Study and Industry Analysis of Oligonucleotide Therapeutics market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.

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