Report Detail

Request for Sample of this report

Other Global Isocitrate Dehydrogenase Inhibitors Market 2019 by Manufacturers, Regions, Type and Application, Forecast to 2024

  • RnM3609556
    • |
  • 22 July, 2019
    • |
  • Global
    • |
  • 101 Pages
    • |
  • GIR (Global Info Research)
    • |
  • Other

Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2.

Scope of the Report:
Specific mutations in the isocitrate dehydrogenase gene IDH1 have been found in several brain tumors including astrocytoma, oligodendroglioma and glioblastoma multiforme, with mutations found in nearly all cases of secondary glioblastomas, which develop from lower-grade gliomas, but rarely in primary high-grade glioblastoma multiforme.Patients whose tumor had an IDH1 mutation had longer survival. Furthermore, mutations of IDH2 and IDH1 were found in up to 20% of cytogenetically normal acute myeloid leukemia (AML).These mutations are known to produce (D)-2-hydroxyglutarate from alpha-ketoglutarate.(D)-2-hydroxyglutarate accumulates to very high concentrations which inhibits the function of enzymes that are dependent on alpha-ketoglutarate.This leads to a hypermethylated state of DNA and histones, which results in different gene expression that can activate oncogenes and inactivate tumor-suppressor genes. Ultimately, this may lead to the types of cancer described above.Isocitrate dehydrogenase inhibition technology can be effectively applied to the cancer market.
The worldwide market for Isocitrate Dehydrogenase Inhibitors is expected to grow at a CAGR of roughly xx% over the next five years, will reach xx million US$ in 2024, from xx million US$ in 2019, according to a new GIR (Global Info Research) study.
This report focuses on the Isocitrate Dehydrogenase Inhibitors in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.

Market Segment by Manufacturers, this report covers
AGIOS
Aslan Pharmaceuticals
Bayer
Beigene
Bristol-Myers Squibb
Celgene
Daiichi Sankyo
Philogen S.p.A.
Tesaro
Tragara/Adastra
Tocagen

Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

Market Segment by Type, covers
IDH1 Mutant Medullary Malignant Tumor
IDH2 Mutant Medullary Malignant Tumor
Others

Market Segment by Applications, can be divided into
DH Inhibitor
FLT3 Inhibitor
Hedgehog Pathway Inhibitor
Others

The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe Isocitrate Dehydrogenase Inhibitors product scope, market overview, market opportunities, market driving force and market risks.
Chapter 2, to profile the top manufacturers of Isocitrate Dehydrogenase Inhibitors, with price, sales, revenue and global market share of Isocitrate Dehydrogenase Inhibitors in 2017 and 2018.
Chapter 3, the Isocitrate Dehydrogenase Inhibitors competitive situation, sales, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the Isocitrate Dehydrogenase Inhibitors breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2014 to 2019.
Chapter 5, 6, 7, 8 and 9, to break the sales data at the country level, with sales, revenue and market share for key countries in the world, from 2014 to 2019.
Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2014 to 2019.
Chapter 12, Isocitrate Dehydrogenase Inhibitors market forecast, by regions, type and application, with sales and revenue, from 2019 to 2024.
Chapter 13, 14 and 15, to describe Isocitrate Dehydrogenase Inhibitors sales channel, distributors, customers, research findings and conclusion, appendix and data source.


Table of Contents

    1 Market Overview

    • 1.1 Isocitrate Dehydrogenase Inhibitors Introduction
    • 1.2 Market Analysis by Type
      • 1.2.1 IDH1 Mutant Medullary Malignant Tumor
      • 1.2.2 IDH2 Mutant Medullary Malignant Tumor
      • 1.2.3 Others
    • 1.3 Market Analysis by Applications
      • 1.3.1 DH Inhibitor
      • 1.3.2 FLT3 Inhibitor
      • 1.3.3 Hedgehog Pathway Inhibitor
      • 1.3.4 Others
    • 1.4 Market Analysis by Regions
      • 1.4.1 North America (United States, Canada and Mexico)
        • 1.4.1.1 United States Market States and Outlook (2014-2024)
        • 1.4.1.2 Canada Market States and Outlook (2014-2024)
        • 1.4.1.3 Mexico Market States and Outlook (2014-2024)
      • 1.4.2 Europe (Germany, France, UK, Russia and Italy)
        • 1.4.2.1 Germany Market States and Outlook (2014-2024)
        • 1.4.2.2 France Market States and Outlook (2014-2024)
        • 1.4.2.3 UK Market States and Outlook (2014-2024)
        • 1.4.2.4 Russia Market States and Outlook (2014-2024)
        • 1.4.2.5 Italy Market States and Outlook (2014-2024)
      • 1.4.3 Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
        • 1.4.3.1 China Market States and Outlook (2014-2024)
        • 1.4.3.2 Japan Market States and Outlook (2014-2024)
        • 1.4.3.3 Korea Market States and Outlook (2014-2024)
        • 1.4.3.4 India Market States and Outlook (2014-2024)
        • 1.4.3.5 Southeast Asia Market States and Outlook (2014-2024)
      • 1.4.4 South America, Middle East and Africa
        • 1.4.4.1 Brazil Market States and Outlook (2014-2024)
        • 1.4.4.2 Egypt Market States and Outlook (2014-2024)
        • 1.4.4.3 Saudi Arabia Market States and Outlook (2014-2024)
        • 1.4.4.4 South Africa Market States and Outlook (2014-2024)
        • 1.4.4.5 Turkey Market States and Outlook (2014-2024)
    • 1.5 Market Dynamics
      • 1.5.1 Market Opportunities
      • 1.5.2 Market Risk
      • 1.5.3 Market Driving Force

    2 Manufacturers Profiles

    • 2.1 AGIOS
      • 2.1.1 Business Overview
      • 2.1.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.1.2.1 Product A
        • 2.1.2.2 Product B
      • 2.1.3 AGIOS Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.2 Aslan Pharmaceuticals
      • 2.2.1 Business Overview
      • 2.2.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.2.2.1 Product A
        • 2.2.2.2 Product B
      • 2.2.3 Aslan Pharmaceuticals Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.3 Bayer
      • 2.3.1 Business Overview
      • 2.3.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.3.2.1 Product A
        • 2.3.2.2 Product B
      • 2.3.3 Bayer Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.4 Beigene
      • 2.4.1 Business Overview
      • 2.4.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.4.2.1 Product A
        • 2.4.2.2 Product B
      • 2.4.3 Beigene Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.5 Bristol-Myers Squibb
      • 2.5.1 Business Overview
      • 2.5.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.5.2.1 Product A
        • 2.5.2.2 Product B
      • 2.5.3 Bristol-Myers Squibb Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.6 Celgene
      • 2.6.1 Business Overview
      • 2.6.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.6.2.1 Product A
        • 2.6.2.2 Product B
      • 2.6.3 Celgene Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.7 Daiichi Sankyo
      • 2.7.1 Business Overview
      • 2.7.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.7.2.1 Product A
        • 2.7.2.2 Product B
      • 2.7.3 Daiichi Sankyo Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.8 Philogen S.p.A.
      • 2.8.1 Business Overview
      • 2.8.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.8.2.1 Product A
        • 2.8.2.2 Product B
      • 2.8.3 Philogen S.p.A. Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.9 Tesaro
      • 2.9.1 Business Overview
      • 2.9.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.9.2.1 Product A
        • 2.9.2.2 Product B
      • 2.9.3 Tesaro Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.10 Tragara/Adastra
      • 2.10.1 Business Overview
      • 2.10.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.10.2.1 Product A
        • 2.10.2.2 Product B
      • 2.10.3 Tragara/Adastra Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)
    • 2.11 Tocagen
      • 2.11.1 Business Overview
      • 2.11.2 Isocitrate Dehydrogenase Inhibitors Type and Applications
        • 2.11.2.1 Product A
        • 2.11.2.2 Product B
      • 2.11.3 Tocagen Isocitrate Dehydrogenase Inhibitors Sales, Price, Revenue, Gross Margin and Market Share (2017-2018)

    3 Global Isocitrate Dehydrogenase Inhibitors Sales, Revenue, Market Share and Competition by Manufacturer (2017-2018)

    • 3.1 Global Isocitrate Dehydrogenase Inhibitors Sales and Market Share by Manufacturer (2017-2018)
    • 3.2 Global Isocitrate Dehydrogenase Inhibitors Revenue and Market Share by Manufacturer (2017-2018)
    • 3.3 Market Concentration Rate
      • 3.3.1 Top 3 Isocitrate Dehydrogenase Inhibitors Manufacturer Market Share in 2018
      • 3.3.2 Top 6 Isocitrate Dehydrogenase Inhibitors Manufacturer Market Share in 2018
    • 3.4 Market Competition Trend

    4 Global Isocitrate Dehydrogenase Inhibitors Market Analysis by Regions

    • 4.1 Global Isocitrate Dehydrogenase Inhibitors Sales, Revenue and Market Share by Regions
      • 4.1.1 Global Isocitrate Dehydrogenase Inhibitors Sales and Market Share by Regions (2014-2019)
      • 4.1.2 Global Isocitrate Dehydrogenase Inhibitors Revenue and Market Share by Regions (2014-2019)
    • 4.2 North America Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 4.3 Europe Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 4.4 Asia-Pacific Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 4.5 South America Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 4.6 Middle East and Africa Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)

    5 North America Isocitrate Dehydrogenase Inhibitors by Country

    • 5.1 North America Isocitrate Dehydrogenase Inhibitors Sales, Revenue and Market Share by Country
      • 5.1.1 North America Isocitrate Dehydrogenase Inhibitors Sales and Market Share by Country (2014-2019)
      • 5.1.2 North America Isocitrate Dehydrogenase Inhibitors Revenue and Market Share by Country (2014-2019)
    • 5.2 United States Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 5.3 Canada Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 5.4 Mexico Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)

    6 Europe Isocitrate Dehydrogenase Inhibitors by Country

    • 6.1 Europe Isocitrate Dehydrogenase Inhibitors Sales, Revenue and Market Share by Country
      • 6.1.1 Europe Isocitrate Dehydrogenase Inhibitors Sales and Market Share by Country (2014-2019)
      • 6.1.2 Europe Isocitrate Dehydrogenase Inhibitors Revenue and Market Share by Country (2014-2019)
    • 6.2 Germany Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 6.3 UK Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 6.4 France Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 6.5 Russia Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 6.6 Italy Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)

    7 Asia-Pacific Isocitrate Dehydrogenase Inhibitors by Country

    • 7.1 Asia-Pacific Isocitrate Dehydrogenase Inhibitors Sales, Revenue and Market Share by Country
      • 7.1.1 Asia-Pacific Isocitrate Dehydrogenase Inhibitors Sales and Market Share by Country (2014-2019)
      • 7.1.2 Asia-Pacific Isocitrate Dehydrogenase Inhibitors Revenue and Market Share by Country (2014-2019)
    • 7.2 China Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 7.3 Japan Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 7.4 Korea Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 7.5 India Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 7.6 Southeast Asia Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)

    8 South America Isocitrate Dehydrogenase Inhibitors by Country

    • 8.1 South America Isocitrate Dehydrogenase Inhibitors Sales, Revenue and Market Share by Country
      • 8.1.1 South America Isocitrate Dehydrogenase Inhibitors Sales and Market Share by Country (2014-2019)
      • 8.1.2 South America Isocitrate Dehydrogenase Inhibitors Revenue and Market Share by Country (2014-2019)
    • 8.2 Brazil Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 8.3 Argentina Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 8.4 Colombia Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)

    9 Middle East and Africa Isocitrate Dehydrogenase Inhibitors by Countries

    • 9.1 Middle East and Africa Isocitrate Dehydrogenase Inhibitors Sales, Revenue and Market Share by Country
      • 9.1.1 Middle East and Africa Isocitrate Dehydrogenase Inhibitors Sales and Market Share by Country (2014-2019)
      • 9.1.2 Middle East and Africa Isocitrate Dehydrogenase Inhibitors Revenue and Market Share by Country (2014-2019)
    • 9.2 Saudi Arabia Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 9.3 Turkey Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 9.4 Egypt Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 9.5 Nigeria Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)
    • 9.6 South Africa Isocitrate Dehydrogenase Inhibitors Sales and Growth Rate (2014-2019)

    10 Global Isocitrate Dehydrogenase Inhibitors Market Segment by Type

    • 10.1 Global Isocitrate Dehydrogenase Inhibitors Sales, Revenue and Market Share by Type (2014-2019)
      • 10.1.1 Global Isocitrate Dehydrogenase Inhibitors Sales and Market Share by Type (2014-2019)
      • 10.1.2 Global Isocitrate Dehydrogenase Inhibitors Revenue and Market Share by Type (2014-2019)
    • 10.2 IDH1 Mutant Medullary Malignant Tumor Sales Growth and Price
      • 10.2.1 Global IDH1 Mutant Medullary Malignant Tumor Sales Growth (2014-2019)
      • 10.2.2 Global IDH1 Mutant Medullary Malignant Tumor Price (2014-2019)
    • 10.3 IDH2 Mutant Medullary Malignant Tumor Sales Growth and Price
      • 10.3.1 Global IDH2 Mutant Medullary Malignant Tumor Sales Growth (2014-2019)
      • 10.3.2 Global IDH2 Mutant Medullary Malignant Tumor Price (2014-2019)
    • 10.4 Others Sales Growth and Price
      • 10.4.1 Global Others Sales Growth (2014-2019)
      • 10.4.2 Global Others Price (2014-2019)

    11 Global Isocitrate Dehydrogenase Inhibitors Market Segment by Application

    • 11.1 Global Isocitrate Dehydrogenase Inhibitors Sales Market Share by Application (2014-2019)
    • 11.2 DH Inhibitor Sales Growth (2014-2019)
    • 11.3 FLT3 Inhibitor Sales Growth (2014-2019)
    • 11.4 Hedgehog Pathway Inhibitor Sales Growth (2014-2019)
    • 11.5 Others Sales Growth (2014-2019)

    12 Isocitrate Dehydrogenase Inhibitors Market Forecast (2019-2024)

    • 12.1 Global Isocitrate Dehydrogenase Inhibitors Sales, Revenue and Growth Rate (2019-2024)
    • 12.2 Isocitrate Dehydrogenase Inhibitors Market Forecast by Regions (2019-2024)
      • 12.2.1 North America Isocitrate Dehydrogenase Inhibitors Market Forecast (2019-2024)
      • 12.2.2 Europe Isocitrate Dehydrogenase Inhibitors Market Forecast (2019-2024)
      • 12.2.3 Asia-Pacific Isocitrate Dehydrogenase Inhibitors Market Forecast (2019-2024)
      • 12.2.4 South America Isocitrate Dehydrogenase Inhibitors Market Forecast (2019-2024)
      • 12.2.5 Middle East and Africa Isocitrate Dehydrogenase Inhibitors Market Forecast (2019-2024)
    • 12.3 Isocitrate Dehydrogenase Inhibitors Market Forecast by Type (2019-2024)
      • 12.3.1 Global Isocitrate Dehydrogenase Inhibitors Sales Forecast by Type (2019-2024)
      • 12.3.2 Global Isocitrate Dehydrogenase Inhibitors Market Share Forecast by Type (2019-2024)
    • 12.4 Isocitrate Dehydrogenase Inhibitors Market Forecast by Application (2019-2024)
      • 12.4.1 Global Isocitrate Dehydrogenase Inhibitors Sales Forecast by Application (2019-2024)
      • 12.4.2 Global Isocitrate Dehydrogenase Inhibitors Market Share Forecast by Application (2019-2024)

    13 Sales Channel, Distributors, Traders and Dealers

    • 13.1 Sales Channel
      • 13.1.1 Direct Marketing
      • 13.1.2 Indirect Marketing
      • 13.1.3 Marketing Channel Future Trend
    • 13.2 Distributors, Traders and Dealers

    14 Research Findings and Conclusion

      15 Appendix

      • 15.1 Methodology

      Summary:
      Get latest Market Research Reports on Isocitrate Dehydrogenase Inhibitors . Industry analysis & Market Report on Isocitrate Dehydrogenase Inhibitors is a syndicated market report, published as Global Isocitrate Dehydrogenase Inhibitors Market 2019 by Manufacturers, Regions, Type and Application, Forecast to 2024. It is complete Research Study and Industry Analysis of Isocitrate Dehydrogenase Inhibitors market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.

      Last updated on

      REPORT YOU MIGHT BE INTERESTED

      Purchase this Report

      		$3,480.00
      		$5,220.00
      		$6,960.00
      		2,773.56
      		4,160.34
      		5,547.12
      		3,232.92
      		4,849.38
      		6,465.84
      		533,240.40
      		799,860.60
      		1,066,480.80
      		290,371.20
      		435,556.80
      		580,742.40
      Credit card Logo
      Sample Question Discount Download PDF

      Related Reports

      Reason to Buy

      • Trusted By Leaders

        Top executives from leading companies purchase research reports from us. 

      • Shop With Confidence

        We assist you with all the pre-sales enquiries related to any report so that you can buy with confidence.

      • Customer Centric

        Need assistance related to your research requirements? We are just a phone call or an email away.

      • Personalized Solutions

        Our experienced research specialists are here to help you locate the right reports for your need.

      • Secure Checkout

        Shop without being worried about safety & security of your transactions.
        •

      Request for Sample of this report

      Reports and Markets

      mcafree

      Contact Us

      +1-352-353-0818 (US)

      info@reportsandmarkets.com

      Support

      EMAIL US

      Newsletter

      KEEP UP TO DATE ON ALL THE LATEST REPORTS


      maxmind_logo