Report Detail

Other Hot Flashes Associated with Prostate Cancer Treatment - Market Insights, Epidemiology, and Market Forecast-2028

  • RnM3869824
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  • 24 January, 2020
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  • Global
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  • 154 Pages
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  • DelveInsight
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  • Other

DelveInsight’s ‘Hot Flashes Associated with Prostate Cancer Treatment—Market Insights, Epidemiology, and Market Forecast—2028’ report deliver an in-depth understanding of the disease, historical and forecasted epidemiology as well as the market trends of Hot Flashes Associated with Prostate Cancer Treatment in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan. The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, the current and forecasted market size of Hot Flashes Associated with Prostate Cancer Treatment from 2017 to 2028 segmented by seven major markets.
Cancer starts when cells in the body activate and grow out of control. In any part of the body, cells can become cancer cells and then can spread to other parts and areas of the body. Prostate cancer arises when cells in the prostate gland start to grow out of control. The prostate is a gland found only in males. It makes some of the fluid which is a part of the semen. For the treatment of prostate cancer ADT is the preferred medication which causes hot flashes which is the major side effect of the treatment.
The hot flash vasomotor phenomena are symptoms that usually result from biochemical disturbances of normal functioning. They might also result in a significance of bilateral orchiectomy, oophorectomy, or pharmacologic therapies. Although these symptoms are not considered life-threatening, hot flashes significantly impact the quality of life (QOL).
Geography Covered
• The United States
• EU5 (Germany, France, Italy, Spain, and the United Kingdom)
• Japan
Study Period: 2017–2028
Hot Flashes Associated with Prostate Cancer Treatment - Disease Understanding and Treatment Algorithm
Hot flashes are described as spontaneous and transient sensations of warmth, varying in severity, which is usually followed by perspiration. Flashing, sweating, palpitations, sleep disturbances, skin blotching, and anxiety are among other symptoms that can accompany hot flashes. The symptoms of hot flashes are a concern of vasomotor variability because of thermoregulatory dysfunction within the hypothalamus and the influence that the hypothalamus has on peripheral vasodilatory mechanisms. Three key neurotransmitters that have been identified in the stimulation of hot flash physiology: endorphins, catechol estrogens, and serotonin. Estrogen and testosterone increase the production of α-endorphins; as sex hormone concentrations decrease, hypothalamic norepinephrine concentrations increase. But the accurate characterization of the severity and frequency of hot flashes can be difficult because they are independent sensations.
Four categories have been used to describe hot flash severity for men. These categories include mild, moderate, severe, and very severe. A mild hot flash is defined as a generalized warmth or a flushed sensation lasting <30 min and drenching sweat demanding a change of clothing or bedding and a bath or shower.
Hot Flashes Associated with Prostate Cancer Treatment Epidemiology
The Hot Flashes Associated with Prostate Cancer Treatment epidemiology division provides insights about historical and current patient pool and forecasted trends for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the incident pool and their trends along with assumptions undertaken.
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology (Total Diagnosed Prevalent Patient Population of Hot Flashes Associated with Prostate Cancer, Prostate Cancer by Stages, Progression from local and regional to advance cases, Hormone-sensitivity cases of Prostate cancer in Advance Stage, ADT use cases in Prostate Cancer, Rate of Hot Flashes Associated with Prostate Cancer, Hot Flashes cases by Severity) scenario of Hot Flashes Associated with Prostate Cancer Treatment in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom) and Japan from 2017 to 2028.
According to DelveInsight, the total Diagnosed Prevalent Patient Population of Hot Flashes Associated with Prostate Cancer in the 7MM was found to be 1,024,536 in 2017. The total Diagnosed Prevalent Patient Population of Hot Flashes Associated with Prostate Cancer in the 7MM is expected to increase during the study period of 2017–2028.
Among 7MM, the United States has the highest total Diagnosed Prevalent Patient Population of Hot Flashes Associated with Prostate Cancer about 430,473 cases in 2017. Among EU5 countries, Germany had the highest number of total Diagnosed Prevalent Patient Population of Hot Flashes Associated with Prostate Cancer with approximately 128,954 cases, followed by France with approximately 126,272 cases in 2017. In Spain, mild, moderate and severe cases for hot flashes were 19,864, 21,519, and 17,735 cases in 2017. In Italy, 83,479 and 24,596 cases were observed using ADT in Hormone-sensitive and ADT use in hormone resistant prostate cancer in 2017.
Hot Flashes Associated with Prostate Cancer Treatment Drug Chapters
This segment of the Hot Flashes Associated with Prostate Cancer Treatment report encloses the detailed analysis of pipeline drug. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.
At present, the therapeutic market size of Hot Flashes Associated with Prostate Cancer in the US is mainly accounted for the management options consisting of pharmacologic treatment options and non-pharmacological therapies.
Pharmacologic treatment options include hormonal therapies (estrogen, Megestrol acetate, Medroxyprogesterone acetate, and cyproterone acetate) and nonhormonal therapies (Clonidine, Venlafaxine, Fluoxetine, Paroxetine, and Gabapentin). Non-pharmacological therapies include vitamin E, soy products, black cohosh acupuncture, and herbal remedies.
Detailed chapters of current therapies and emerging therapies, such as Zuclomiphene Citrate (Veru-944) by Veru Pharma have also been provided in the report.
Hot Flashes Associated with Prostate Cancer Treatment Market Outlook
The Hot Flashes Associated with Prostate Cancer Treatment market outlook of the report helps to build a detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.
According to DelveInsight, the market for Hot Flashes Associated with Prostate Cancer Treatment in 7MM was found to be approximately USD 162.64 Million in 2017.
Hot Flashes Associated with Prostate Cancer Treatment market size in the United States accounted for 45% of the total market in 2017. The US led the market in 2017, followed by the EU5 and Japan, respectively. Due to the increasing cases of this disease in the region, the Hot Flashes Associated with Prostate Cancer Treatment treatment market in the US is expected to dominate the market during the forecast period (2019–2028).
Hot Flashes Associated with Prostate Cancer Treatment Drugs Uptake
This section focusses on the rate of uptake of the potential drugs that will get launched in the market during the study period from 2017 to 2028. The analysis covers market uptake by the drug; patient uptake by therapies, and sales of each drug.
The dynamics of Hot Flashes Associated with Prostate Cancer Treatment market is anticipated to change in the coming years owing to the expected launch of emerging therapy, such as Zuclomiphene Citrate (Veru-944) by Veru Pharma and others in the Hot Flashes Associated with Prostate Cancer Treatment market by 2028.
Hot Flashes Associated with Prostate Cancer Treatment Report Insights
• Patient Population of Hot Flashes Associated with Prostate Cancer Treatment
• Therapeutic Approaches
• Pipeline Analysis
• Market Size and Trends
• Market Opportunities
• Impact of upcoming Therapies
Hot Flashes Associated with Prostate Cancer Treatment Report Key Strengths
• 10-Year Forecast
• 7MM Coverage
• Epidemiology Segmentation
• Drugs Uptake
• Highly Analyzed Market
• Key Cross Competition

Hot Flashes Associated with Prostate Cancer Treatment Report Assessment
• Current Treatment Practices
• Unmet Needs
• Detailed Pipeline Product Profiles
• Market Attractiveness
• Market Drivers and Barriers

Key Benefits
• This DelveInsight report will help to develop Business Strategies by understanding the trends shaping and driving Hot Flashes Associated with Prostate Cancer Treatment market
• Organize sales and marketing efforts by identifying the best opportunities for Hot Flashes Associated with Prostate Cancer Treatment market
• To understand the future market competition in the Hot Flashes Associated with Prostate Cancer Treatment market


1. Key Insights

    2. Region-Wise Market Share (%) Distribution of Hot Flashes Associated with Prostate Cancer Treatment in 2017

      3. Region-Wise Market Share (%) Distribution of Hot Flashes Associated with Prostate Cancer Treatment in 2028

        4. Disease Background and Overview: Hot Flashes Associated with Prostate Cancer Treatment

        • 4.1. Introduction
        • 4.2. Risk Factors for Prostate Cancer
        • 4.3. Symptoms
        • 4.4. Stages and Grades
        • 4.5. Pathophysiology
        • 4.6. Histopathology
        • 4.7. Diagnosis

        5. Androgen Deprived Therapy (ADT)-Associated Prostate Cancer Treatment

        • 5.1. Treatment to lower testicular androgen levels
          • 5.1.1. Orchiectomy
          • 5.1.2. Luteinizing hormone-releasing hormone (LHRH) agonists
          • 5.1.3. Luteinizing hormone-releasing hormone (LHRH) antagonists
        • 5.2. Treatment to lower androgen levels from the adrenal glands
        • 5.3. Drugs that stop androgens from working
          • 5.3.1. Anti-androgens
          • 5.3.2. Newer anti-androgens

        6. Recognized Establishments

          7. Epidemiology and Patient Population

          • 7.1. Key Findings
          • 7.2. Cases of Hot Flashes Associated with Prostate Cancer Treatment in the 7MM

          8. Country Wise-Epidemiology of Hot Flashes Associated with Prostate Cancer Treatment

          • 8.1. United States
            • 8.1.1. Assumptions and Rationale
            • 8.1.2. Mortality adjusted Diagnosed Prevalent Population of Prostate Cancer in the United States
            • 8.1.3. Prostate Cancer by Stages in the United States
            • 8.1.4. Progression from local and regional to advance stage in the United States
            • 8.1.5. Hormone-sensitivity of Prostate cancer in Advance Stage in the United States
            • 8.1.6. ADT use in Prostate Cancer in the United States
            • 8.1.7. Rate of Hot Flashes Associated with Prostate Cancer Treatment in the United States
            • 8.1.8. Hot Flashes by Severity in the United States
          • 8.2. EU5 Countries
            • 8.2.1. Assumptions and Rationale
          • 8.3. Germany
            • 8.3.1. Mortality adjusted Diagnosed Prevalent Population of Prostate Cancer in Germany
            • 8.3.2. Prostate Cancer by Stages in Germany
            • 8.3.3. Progression from local and regional to advance stage in Germany
            • 8.3.4. Hormone-sensitivity of Prostate cancer in Advance Stage in Germany
            • 8.3.5. ADT use in Prostate Cancer in Germany
            • 8.3.6. Rate of Hot Flashes Associated with Prostate Cancer Treatment in Germany
            • 8.3.7. Hot Flashes by Severity in Germany
          • 8.4. France
            • 8.4.1. Mortality adjusted Diagnosed Prevalent Population of Prostate Cancer in France
            • 8.4.2. Prostate Cancer by Stages in France
            • 8.4.3. Progression from local and regional to advance stage in France
            • 8.4.4. Hormone-sensitivity of Prostate cancer in Advance Stage in France
            • 8.4.5. ADT use in Prostate Cancer in France
            • 8.4.6. Rate of Hot Flashes Associated with Prostate Cancer Treatment in France
            • 8.4.7. Hot Flashes by Severity in France
          • 8.5. Italy
            • 8.5.1. Mortality adjusted Diagnosed Prevalent Population of Prostate Cancer in Italy
            • 8.5.2. Prostate Cancer by Stages in Italy
            • 8.5.3. Progression from local and regional to advance stage in Italy
            • 8.5.4. Hormone-sensitivity of Prostate cancer in Advance Stage in Italy
            • 8.5.5. ADT use in Prostate Cancer in Italy
            • 8.5.6. Rate of Hot Flashes Associated with Prostate Cancer Treatment in Italy
            • 8.5.7. Hot Flashes by Severity in Italy
          • 8.6. Spain
            • 8.6.1. Mortality adjusted Diagnosed Prevalent Population of Prostate Cancer in Spain
            • 8.6.2. Prostate Cancer by Stages in Spain
            • 8.6.3. Progression from local and regional to advance stage in Spain
            • 8.6.4. Hormone-sensitivity of Prostate cancer in Advance Stage in Spain
            • 8.6.5. ADT use in Prostate Cancer in Spain
            • 8.6.6. Rate of Hot Flashes Associated with Prostate Cancer Treatment in Spain
            • 8.6.7. Hot Flashes by Severity in Spain
          • 8.7. United Kingdom
            • 8.7.1. Mortality adjusted Diagnosed Prevalent Population of Prostate Cancer in the United Kingdom
            • 8.7.2. Prostate Cancer by Stages in the United Kingdom
            • 8.7.3. Progression from local and regional to advance stage in the United Kingdom
            • 8.7.4. Hormone-sensitivity of Prostate cancer in Advance Stage in the United Kingdom
            • 8.7.5. ADT use in Prostate Cancer in the United Kingdom
            • 8.7.6. Rate of Hot Flashes Associated with Prostate Cancer Treatment in the United Kingdom
            • 8.7.7. Hot Flashes by Severity in the United Kingdom
          • 8.8. Japan
            • 8.8.1. Assumptions and Rationale
            • 8.8.2. Mortality adjusted Diagnosed Prevalent Population of Prostate Cancer in Japan
            • 8.8.3. Prostate Cancer by Stages in Japan
            • 8.8.4. Progression from local and regional to advance stage in Japan
            • 8.8.5. Hormone-sensitivity of Prostate cancer in Advance Stage in Japan
            • 8.8.6. ADT use in Prostate Cancer in Japan
            • 8.8.7. Rate of Hot Flashes Associated with Prostate Cancer Treatment in Japan
            • 8.8.8. Hot Flashes by Severity in Japan
            • 8.8.9. Rate of Hot Flashes Associated with Prostate Cancer Treatment in Japan
            • 8.8.10. Hot Flashes by Severity in Japan

          9. Treatment of Hot Flashes in Men

          • 9.1. Pharmacologic Treatment
            • 9.1.1. Hormonal therapies
          • 9.2. Nonhormonal therapies
          • 9.3. Nonpharmacologic Therapies

          10. Unmet Needs

            11. Emerging Drug

            • 11.1. Zuclomiphene citrate (Veru-944): Veru Pharma
              • 11.1.1. Product Description
              • 11.1.2. Other Developmental Activities
              • 11.1.3. Clinical Development
              • 11.1.4. Product Profile

            12. What Experts Say?

              13. Hot Flashes Associated with Prostate Cancer Treatment: 7 Major Market Analysis

              • 13.1. Key Findings
              • 13.2. Hot Flashes Associated with Prostate Cancer Treatment Market Overview at a Glance
                • 13.2.1. Market Share (%) Distribution of Hot Flashes Associated with Prostate Cancer Treatment in 2017
                • 13.2.2. Market Share (%) Distribution of Hot Flashes Associated with Prostate Cancer Treatment in 2028
              • 13.3. Market Size of Hot Flashes Associated with Prostate Cancer Treatment in the 7MM Countries

              14. The United States Market Outlook

              • 14.1. United States
                • 14.1.1. Total Market size of Hot Flashes Associated with Prostate Cancer Treatment
                • 14.1.2. Market Size by Therapies

              15. EU-5 Countries: Market Outlook

              • 15.1. Germany
                • 15.1.1. Total Market size of Hot Flashes Associated with Prostate Cancer Treatment
                • 15.1.2. Market Size by Therapies

              16. France

              • 16.1.1. Total Market size of Hot Flashes Associated with Prostate Cancer Treatment
              • 16.1.2. Market Size by Therapies

              17. Italy

              • 17.1.1. Total Market Size of Hot Flashes Associated with Prostate Cancer Treatment
              • 17.1.2. Market Size by Therapies

              18. Spain

              • 18.1.1. Total Market Size of Hot Flashes Associated with Prostate Cancer Treatment
              • 18.1.2. Market Size by Therapies

              19. United Kingdom

              • 19.1.1. Total Market Size of Hot Flashes Associated with Prostate Cancer Treatment
              • 19.1.2. Market Size by Therapies

              20. Japan: Market Outlook

              • 20.1. Japan market Size
                • 20.1.1. Total Market Size of Hot Flashes Associated with Prostate Cancer Treatment
                • 20.1.2. Market Size by Therapies

              21. Market Drivers

                22. Market Barriers

                  23. Appendix

                  • 23.1. Report Methodology

                  24. DelveInsight Capabilities

                    25. Disclaimer

                      26. About DelveInsight

                      Summary:
                      Get latest Market Research Reports on Hot Flashes Associated with Prostate Cancer Treatment. Industry analysis & Market Report on Hot Flashes Associated with Prostate Cancer Treatment is a syndicated market report, published as Hot Flashes Associated with Prostate Cancer Treatment - Market Insights, Epidemiology, and Market Forecast-2028. It is complete Research Study and Industry Analysis of Hot Flashes Associated with Prostate Cancer Treatment market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.

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