According to our (Global Info Research) latest study, the global Fermentation Defoamer market size was valued at US$ 375 million in 2025 and is forecast to a readjusted size of US$ 428 million by 2032 with a CAGR of 2.0% during review period.
A fermentation defoamer is a specialized chemical additive used in industrial fermentation (like making alcohol, enzymes, amino acids) to prevent, control, and eliminate excessive foam, which is caused by microbial activity, gas release, and agitation, thereby improving efficiency, preventing overflow, and ensuring consistent product quality. They work by destroying the foam's stable structure, reducing surface tension, and lowering gas solubility, allowing processes to run smoothly without losing valuable broth or risking contamination. In 2025, global Fermentation Defoamer production reached approximately 53 K MT.
Fermentation defoamers are process additives used to control and suppress foam formation in aerobic and anaerobic fermentation systems. Foam arises from microbial metabolism, gas sparging, and the presence of proteins, polysaccharides, and surfactants in the broth, which can reduce oxygen transfer efficiency, contaminate exhaust filters, and cause product loss or process instability. Defoamers are formulated from silicone-based, oil-based, polyether-based, or bio-based components, and are designed to rapidly break surface foam while maintaining compatibility with microorganisms and downstream purification. They are widely used in the production of antibiotics, amino acids, enzymes, organic acids, vitamins, yeast, vaccines, and bio-based chemicals, where stable, high-density fermentation is essential for productivity.
Key market drivers for fermentation defoamers stem from the expansion of the biotechnology, pharmaceutical, and industrial fermentation industries. Rising global demand for biologics, biosimilars, and microbial-derived ingredients is leading to higher fermentation volumes and more intensive operating conditions, which in turn increase foam control requirements. In industrial biotechnology, the growth of biofuels, bioplastics, and bio-based intermediates also supports demand for defoamers that can perform reliably in large-scale, continuous or fed-batch systems. Producers are under pressure to maximize yield, reduce batch failure risk, and improve oxygen transfer efficiency, making effective defoaming a critical process optimization tool rather than a simple auxiliary chemical.
Market trends in fermentation defoamers increasingly emphasize process compatibility, regulatory compliance, and sustainability. Manufacturers are developing low-toxicity, low-residue, and food- or pharma-grade defoamers that minimize interference with cell growth and simplify downstream purification. There is also a growing shift toward silicone-free and bio-based defoamers, particularly in food fermentation and pharmaceutical applications where regulatory scrutiny is high. In parallel, smarter dosing strategies—such as automated foam sensing and controlled addition—are improving defoamer efficiency and reducing overall consumption. Overall, the market is evolving toward high-performance, application-specific defoaming solutions that support scalable, compliant, and cost-efficient fermentation processes.
This report is a detailed and comprehensive analysis for global Fermentation Defoamer market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global Fermentation Defoamer market size and forecasts, in consumption value ($ Million), sales quantity (K MT), and average selling prices (USD/MT), 2021-2032
Global Fermentation Defoamer market size and forecasts by region and country, in consumption value ($ Million), sales quantity (K MT), and average selling prices (USD/MT), 2021-2032
Global Fermentation Defoamer market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (K MT), and average selling prices (USD/MT), 2021-2032
Global Fermentation Defoamer market shares of main players, shipments in revenue ($ Million), sales quantity (K MT), and ASP (USD/MT), 2021-2026
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for Fermentation Defoamer
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global Fermentation Defoamer market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include DuPont, Momentive, Wacker, Shin-Etsu, PennWhite, KCC Basildon Chemicals, Blackburn Chemicals, Accepta, ADDAPT Chemicals, Emerald Performance Materials, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market Segmentation
Fermentation Defoamer market is split by Type and by Application. For the period 2021-2032, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Type
Silicone Defoamer
Polyether Defoamer
Polyether Modified Silicon Defoamer
Other
Market segment by Feature
Anti-foaming Type
Defoaming Type
Dual-effect Anti-foaming Type
Market segment by Channel
Direct Selling
Distribution
Market segment by Application
Food & Beverage
Biofuel
Pharmaceutical
Feed
Other
Major players covered
DuPont
Momentive
Wacker
Shin-Etsu
PennWhite
KCC Basildon Chemicals
Blackburn Chemicals
Accepta
ADDAPT Chemicals
Emerald Performance Materials
Hydrite Chemical (Organic Defoamer)
Elkem Silicones
SIXIN
Yantai Thingking Finechem Technology
Huajin Chemical
Sanye Fine Chemical
Defeng
Market segment by region, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe Fermentation Defoamer product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of Fermentation Defoamer, with price, sales quantity, revenue, and global market share of Fermentation Defoamer from 2021 to 2026.
Chapter 3, the Fermentation Defoamer competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the Fermentation Defoamer breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2021 to 2032.
Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2021 to 2032.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2021 to 2026.and Fermentation Defoamer market forecast, by regions, by Type, and by Application, with sales and revenue, from 2027 to 2032.
Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
Chapter 13, the key raw materials and key suppliers, and industry chain of Fermentation Defoamer.
Chapter 14 and 15, to describe Fermentation Defoamer sales channel, distributors, customers, research findings and conclusion.
Summary:
Get latest Market Research Reports on Fermentation Defoamer. Industry analysis & Market Report on Fermentation Defoamer is a syndicated market report, published as Global Fermentation Defoamer Market 2026 by Manufacturers, Regions, Type and Application, Forecast to 2032. It is complete Research Study and Industry Analysis of Fermentation Defoamer market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.