Report Detail

Biotechnology Cell-Based Assays Global Market – Forecast To 2025

  • RnM3570742
  • |
  • 12 March, 2020
  • |
  • Global
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  • 467 Pages
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  • IQ4I Research & Consultancy
  • |
  • Biotechnology

Cell-based assays refer to use of live cells in experiments, to analyze or understand various accepts of response by organism against an external therapeutic or toxic agent. The demand for cost-effective and relevant research tool in drug discovery, development and manufacturing, toxicity testing, ecotoxicology, biosafety and biocompatibility of cosmetics and chemicals is increasing interest in cell-based assays. The rise in research and the approvals of biologics and biosimilars are increasing utilization of cell-based assay as a tool for ensuring safety and potency of the product. The factors driving the market are rising use of the cell-based assay in drug discovery and development, increasing focus on biologics, technological advancements favoring the adoption of cell-based assays, the growing availability of funds for research. Whereas, factors such as lack of skilled professionals, ethical concerns over the use of raw materials from animal sources, high cost of instruments, lack of standardization, consistency and reproducibility issues are restraining the market growth.
According to IQ4I analysis, the Cell-based assays global market is is expected to grow at a CAGR of 8.0% to reach 20,053.4 million by 2025. Cell-based assays or bioassays are often an integral part of drug development in the pharma and biotech industry, which are a key component of preclinical, clinical and drug manufacturing processes. Other areas of application include, basic research, diagnostics and medical device testing, agro product and environmental testing, cosmetic testing, food and beverages testing and chemical and material testing. The Cell-based assays global market is segmented based on the products, applications, and geography. The Cell-based assays market by Products is segmented into Consumables, Instruments, and Software & Services. Among which, Consumables market commanded the largest share in 2018 growing at high single digit CAGR from 2018 to 2025.
The consumables market is further sub-segmented into assay kits, cells, microplates, reagents and others, among which reagents commanded the largest market share and is expected to grow at high CAGR from 2018 to 2025. The assay kits are further classified based on research needs into reporter gene assay, second messenger, cell-growth assay, cell death assay, motility assays and others. Among which reporter gene assay commanded the largest revenue in 2018 and it is expected to grow at a strong CAGR, where, the increasing use of these assays in study of gene regulation, diagnostics, cell dynamics and development are factors driving the market. The cells market is sub-segmented based on source into primary cells, cell lines and stem cells, where, cell lines commanded the largest revenue in 2018 and the market is expected to grow at double digit CAGR from 2018 to 2025. The demand for cell lines in research because of the advantages such as, cost-effectiveness, ease of use, unlimited supply and bypassing of ethical concerns associated with the use of products of animal origin and human tissue are driving its growth. The emerging trend of a large number of service providers offering ready to use cell-based assay kits along with custom assay, cells and reagent development capabilities for research institutes, pharma, and biotech clients to carry out clinical and non-clinical development of pharmaceuticals, research activities, product testing to comply with regulatory requirements.
Microplate readers, liquid handling devices, flow cytometers, automated cell counters, microfluidic chips and cell microarrays, high throughput screening, high content screening, microscopes, and other instruments constitute the cell-based assays instrument market. Among which, microplate readers commanded the largest revenue in 2018, the market is expected to grow at a mid single digit CAGR from 2018 to 2025. With the advancements in label-free imaging and phenotypic screening methods in research, the microscopes market is expected to grow at a mid single digit CAGR from 2018 to 2025.
The cell-based assays geographical market consists of North America, Europe, Asia-Pacific and RoW, where North America dominates the market due to the presence of a large number of pharma-biotech companies, and investments for research from both public and private players. Asia-Pacific region is expected to show high single digit CAGR growth from 2018 to 2025, due to the presence of a large number of CROs and the emergence of this region as the manufacturing hub for biologics drugs.
Some of the key players in Cell-based assays global market are Danaher Corp. (U.S.), ThermoFisher Scientific (U.S.), Merck KGaA (Germany), Becton, Dickinson and Company (U.S.), Perkin Elmer, Inc. (U.S.), Lonza Group (Switzerland), Corning, Inc. (U.S.), Tecan Group (Switzerland), Bio-Rad Laboratories, Inc. (U.S.), Biotek Instruments (U.S.), Promega Corporation (U.S.) and GE Healthcare (U.S.).
The report provides an in-depth market analysis of the above-mentioned segments across the following regions:
• North America
• Europe
• Asia-Pacific
• Rest of the World (RoW)


1 EXECUTIVE SUMMARY 29

    2 INTRODUCTION 34

    • 2.1 KEY TAKEAWAYS 34
    • 2.2 SCOPE OF THE REPORT 35
    • 2.3 REPORT DESCRIPTION 35
    • 2.4 MARKETS COVERED 37
    • 2.5 STAKEHOLDERS 39
    • 2.6 RESEARCH METHODOLOGY 40
      • 2.6.1 MARKET CRACKDOWN AND DATA TRIANGULATION 44
      • 2.6.2 SECONDARY SOURCES 45
      • 2.6.3 KEY DATA POINTS FROM SECONDARY SOURCES 46
      • 2.6.4 PRIMARY SOURCES 47
      • 2.6.5 KEY DATA POINTS FROM PRIMARY SOURCES 47
      • 2.6.6 ASSUMPTIONS 47

    3 MARKET ANALYSIS 49

    • 3.1 INTRODUCTION 49
    • 3.2 MARKET SEGMENTATION 50
    • 3.3 FACTORS INFLUENCING MARKET 52
      • 3.3.1 DRIVERS AND OPPORTUNITIES 53
        • 3.3.1.1 Rising use of cell-based assays in drug discovery and development 53
        • 3.3.1.2 Increasing focus on biologics 53
        • 3.3.1.3 Technological advancements favoring the adoption of cell-based assays 54
        • 3.3.1.4 The growing availability of funds for research 56
      • 3.3.2 RESTRAINTS AND THREATS 57
        • 3.3.2.1 Maintaining consistency, reproducibility of assays and lack of standardization 57
        • 3.3.2.2 Lack of skilled professionals 57
        • 3.3.2.3 The high cost of instruments and special research materials 58
        • 3.3.2.4 Ethical concern over the use of raw materials from animal sources 59
    • 3.4 PORTER’S FIVE FORCE ANALYSIS 59
      • 3.4.1 THREAT OF NEW ENTRANTS 60
      • 3.4.2 THREAT OF SUBSTITUTES 61
      • 3.4.3 RIVALRY AMONG EXISTING COMPETITORS 61
      • 3.4.4 BARGAINING POWER OF SUPPLIERS 62
      • 3.4.5 BARGAINING POWER OF BUYERS 62
    • 3.5 TECHNOLOGY ADVANCEMENTS 63
      • 3.5.1 PREDICTIVE TOXICOLOGY 63
      • 3.5.2 3D BIO-PRINTING 63
      • 3.5.3 GENE EDITING TOOLS IN DRUG DISCOVERY 64
      • 3.5.4 VIRTUAL SCREENING, ARTIFICIAL INTELLIGENCE/MACHINE

    LEARNING IN DRUG DISCOVERY 64

    • 3.6 REGULATORY AFFAIRS 65
      • 3.6.1 UNITED STATES 65
      • 3.6.2 EUROPE 66
      • 3.6.3 JAPAN 67
      • 3.6.4 ISO STANDARDS 68
      • 3.6.5 OECD GUIDELINES FOR TESTING CHEMICALS 68
    • 3.7 DEALS 69
    • 3.8 MARKET SHARE ANALYSIS 79
      • 3.8.1 MARKET SHARE ANALYSIS: CELL-BASED ASSAYS MAJOR PLAYERS 79
    • 3.9 COST OF DEVICES 83

    4 CELL-BASED ASSAYS GLOBAL MARKET, BY PRODUCTS 91

    • 4.1 INTRODUCTION 91
    • 4.2 CONSUMABLES 94
      • 4.2.1 ASSAY KITS 98
        • 4.2.1.1 Reporter gene assay 102
        • 4.2.1.2 Second messenger assay 106
        • 4.2.1.3 Cell growth assay 109
        • 4.2.1.4 Cell death assay/cytotoxic assay 113
        • 4.2.1.5 Cell motility assays 120
        • 4.2.1.6 Others 127
      • 4.2.2 CELLS 129
        • 4.2.2.1 Cell lines 132
        • 4.2.2.2 Primary cells 134
        • 4.2.2.3 Stem cells 137
      • 4.2.3 MICROPLATES 140
      • 4.2.4 REAGENTS 149
      • 4.2.5 OTHERS 153
    • 4.3 INSTRUMENTS 154
      • 4.3.1 MICROPLATE READERS 159
      • 4.3.2 LIQUID HANDLING SYSTEMS 162
      • 4.3.3 FLOWCYTOMETER 165
      • 4.3.4 AUTOMATED CELL COUNTERS 168
      • 4.3.5 MICROFLUIDIC CHIPS & CELL MICROARRAY 170
      • 4.3.6 HIGH THROUGHPUT SCREENING 174
      • 4.3.7 HIGH CONTENT SCREENING 176
      • 4.3.8 MICROSCOPES 179
      • 4.3.9 OTHERS 183
    • 4.4 SOFTWARE AND SERVICES 184

    5 CELL-BASED ASSAYS GLOBAL MARKET, BY APPLICATIONS 195

    • 5.1 INTRODUCTION 195
    • 5.2 PHARMA AND BIOTECH 199
      • 5.2.1 DRUG DISCOVERY 204
      • 5.2.2 DRUG DEVELOPMENT 209
      • 5.2.3 DRUG MANUFACTURING 216
    • 5.3 BASIC RESEARCH 223
    • 5.4 DIAGNOSTICS AND MEDICAL DEVICES 226
    • 5.5 AGRO AND ENVIRONMENTAL TESTING 229
    • 5.6 COSMETICS TESTING 233
    • 5.7 FOOD AND BEVERAGES 237
    • 5.8 CHEMICALS AND MATERIALS 239
    • 5.9 OTHERS 240

    6 REGIONAL ANALYSIS 242

    • 6.1 INTRODUCTION 242
    • 6.2 NORTH AMERICA 247
      • 6.2.1 THE U.S. 261
      • 6.2.2 REST OF NORTH AMERICA 266
    • 6.3 EUROPE 271
      • 6.3.1 GERMANY 285
      • 6.3.2 U.K. 290
      • 6.3.3 FRANCE 294
      • 6.3.4 REST OF EUROPE 298
    • 6.4 APAC 303
      • 6.4.1 CHINA 316
      • 6.4.2 JAPAN 321
      • 6.4.3 INDIA 324
      • 6.4.4 REST OF APAC 329
    • 6.5 ROW 333
      • 6.5.1 BRAZIL 347
      • 6.5.2 REST OF LATAM 351
      • 6.5.3 MIDDLE EAST & OTHERS 355

    7 COMPETITIVE LANDSCAPE 359

    • 7.1 INTRODUCTION 359
    • 7.2 NEW PRODUCT LAUNCH 360
    • 7.3 AGREEMENTS & COLLABORATIONS 367
    • 7.4 ACQUISITIONS 371
    • 7.5 OTHERS 373

    8 MAJOR PLAYER PROFILES 376

    • 8.1 BECTON, DICKINSON AND COMPANY 376
      • 8.1.1 OVERVIEW 376
      • 8.1.2 FINANCIALS 378
      • 8.1.3 PRODUCT PORTFOLIO 381
      • 8.1.4 KEY DEVELOPMENTS 383
      • 8.1.5 BUSINESS STRATEGY 383
      • 8.1.6 SWOT ANALYSIS 384
    • 8.2 BIO-RAD LABORATORIES 385
      • 8.2.1 OVERVIEW 385
      • 8.2.2 FINANCIALS 387
      • 8.2.3 PRODUCT PORTFOLIO 389
      • 8.2.4 KEY DEVELOPMENTS 390
      • 8.2.5 BUSINESS STRATEGY 391
      • 8.2.6 SWOT ANALYSIS 392
    • 8.3 BIOTEK INSTRUMENTS, INC 393
      • 8.3.1 OVERVIEW 393
      • 8.3.2 FINANCIALS 393
      • 8.3.3 PRODUCT PORTFOLIO 393
      • 8.3.4 KEY DEVELOPMENTS 395
      • 8.3.5 BUSINESS STRATEGY 396
      • 8.3.6 SWOT ANALYSIS 397
    • 8.4 CORNING INC. 398
      • 8.4.1 OVERVIEWS 398
      • 8.4.2 FINANCIALS 400
      • 8.4.3 PRODUCT PORTFOLIO 402
      • 8.4.4 KEY DEVELOPMENTS 405
      • 8.4.5 BUSINESS STRATEGY 406
      • 8.4.6 SWOT ANALYSIS 407
    • 8.5 DANAHER CORPORATION 408
      • 8.5.1 OVERVIEW 408
      • 8.5.2 FINANCIALS 410
      • 8.5.3 PRODUCT PORTFOLIO 412
      • 8.5.4 KEY DEVELOPMENTS 415
      • 8.5.5 BUSINESS STRATEGY 417
      • 8.5.6 SWOT ANALYSIS 418
    • 8.6 LONZA GROUP LTD 419
      • 8.6.1 OVERVIEW 419
      • 8.6.2 FINANCIALS 421
      • 8.6.3 PRODUCT PORTFOLIO 423
      • 8.6.4 KEY DEVELOPMENTS 427
      • 8.6.5 BUSINESS STRATEGY 429
      • 8.6.6 SWOT ANALYSIS 430
    • 8.7 MERCK KGAA 431
      • 8.7.1 OVERVIEW 431
      • 8.7.2 FINANCIALS 433
      • 8.7.3 PRODUCT PORTFOLIO 435
      • 8.7.4 KEY DEVELOPMENTS 438
      • 8.7.5 BUSINESS STRATEGY 439
      • 8.7.6 SWOT ANALYSIS 440
    • 8.8 PERKINELMER, INC 441
      • 8.8.1 OVERVIEW 441
      • 8.8.2 FINANCIALS 443
      • 8.8.3 PRODUCT PORTFOLIO 445
      • 8.8.4 KEY DEVELOPMENTS 446
      • 8.8.5 BUSINESS STRATEGY 447
      • 8.8.6 SWOT ANALYSIS 448
    • 8.9 TECAN TRADING AG 449
      • 8.9.1 OVERVIEW 449
      • 8.9.2 FINANCIALS 451
      • 8.9.3 PRODUCT PORTFOLIO 453
      • 8.9.4 KEY DEVELOPMENTS 455
      • 8.9.5 BUSINESS STRATEGY 456
      • 8.9.6 SWOT ANALYSIS 457
    • 8.10 THERMO FISHER SCIENTIFIC 458
      • 8.10.1 OVERVIEW 458
      • 8.10.2 FINANCIALS 460
      • 8.10.3 PRODUCT PORTFOLIO 462
      • 8.10.4 KEY DEVELOPMENTS 464
      • 8.10.5 BUSINESS STRATEGY 465

    Summary:
    Get latest Market Research Reports on Cell-Based Assays . Industry analysis & Market Report on Cell-Based Assays is a syndicated market report, published as Cell-Based Assays Global Market – Forecast To 2025. It is complete Research Study and Industry Analysis of Cell-Based Assays market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.

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