Report Detail

Biotechnology Polymerase Chain Reaction (PCR) Global Market - Forecast to 2025

  • RnM3855616
  • |
  • 12 March, 2020
  • |
  • Global
  • |
  • 532 Pages
  • |
  • IQ4I Research & Consultancy
  • |
  • Biotechnology

1 EXECUTIVE SUMMARY 32

    2 INTRODUCTION 38

    • 2.1 KEY TAKEAWAYS 38
    • 2.2 REPORT DESCRIPTION 39
    • 2.3 MARKETS COVERED 41
    • 2.4 STAKEHOLDERS 45
    • 2.5 RESEARCH METHODOLOGY 45
      • 2.5.1 MARKET SIZE ESTIMATION 47
      • 2.5.2 MARKET BREAKDOWN AND DATA TRIANGULATION 49
      • 2.5.3 SECONDARY SOURCES 50
      • 2.5.4 KEY DATA POINTS FROM SECONDARY SOURCES 51
      • 2.5.5 PRIMARY SOURCES 52
      • 2.5.6 KEY DATA POINTS FROM PRIMARY SOURCES 52
      • 2.5.7 ASSUMPTIONS 53

    3 MARKET ANALYSIS 54

    • 3.1 INTRODUCTION 54
    • 3.2 MARKET SEGMENTATION 56
    • 3.3 FACTORS INFLUENCING MARKET 58
      • 3.3.1 DRIVERS AND OPPORTUNITIES 59
        • 3.3.1.1 Requirement of early detection of disease 59
        • 3.3.1.2 Increasing demand for PCR in genetic and molecular testing 60
        • 3.3.1.3 High prevalence of infectious diseases 62
        • 3.3.1.4 Increasing qpcr based food safety testing 63
        • 3.3.1.5 Expiry of key players PCR patents 64
        • 3.3.1.6 Growing demand for rapid diagnostic tests 64
        • 3.3.1.7 Increasing use of companion diagnostics 65
        • 3.3.1.8 Technological advances 66
      • 3.3.2 RESTRAINTS AND THREATS 68
        • 3.3.2.1 High cost of commercial PCR assays in clinical diagnostics 68
        • 3.3.2.2 Lack of awareness and requirement of skilled labor 68
        • 3.3.2.3 Development of alternate technologies 69
        • 3.3.2.4 Stringent regulatory framework 70
    • 3.4 REGULATORY AFFAIRS 71
      • 3.4.1 INTERNATIONAL ORGANIZATION FOR STANDARDIZATION 71
        • 3.4.1.1 ISO 9001: 2015 quality management system 71
      • 3.4.2 U.S. 71
      • 3.4.3 CANADA 72
      • 3.4.4 EUROPE 73
      • 3.4.5 CHINA 73
      • 3.4.6 INDIA 73
      • 3.4.7 JAPAN 74
    • 3.5 PORTER’S FIVE FORCE ANALYSIS 75
      • 3.5.1 THREAT OF NEW ENTRANTS 76
      • 3.5.2 THREAT OF SUBSTITUTES 76
      • 3.5.3 BARGAINING POWER OF SUPPLIERS 77
      • 3.5.4 BARGAINING POWER OF BUYERS 77
      • 3.5.5 COMPETITIVE RIVALRY 77
    • 3.6 SUPPLY CHAIN ANALYSIS 79
    • 3.7 MARKET SHARE ANALYSIS BY MAJOR PLAYERS 81
      • 3.7.1 PCR GLOBAL MARKET SHARE ANALYSIS 81
    • 3.8 PATENT TRENDS 84
    • 3.9 REFURBISHED DEVICES 85
    • 3.10 FUNDING SCENARIO 87

    4 PCR GLOBAL MARKET, BY TECHNIQUES 90

    • 4.1 INTRODUCTION 90
    • 4.2 STANDARD PCR 93
    • 4.3 REAL TIME PCR/QPCR 96
    • 4.4 REVERSE TRANSCRIPTASE PCR 100
    • 4.5 DIGITAL PCR 103
    • 4.6 ASSEMBLY PCR 107
    • 4.7 MULTIPLEX PCR 110
    • 4.8 HOT START PCR 113
    • 4.9 OTHER PCR TECHNIQUES 116

    5 PCR GLOBAL MARKET, BY PRODUCT 125

    • 5.1 INTRODUCTION 125
    • 5.2 INSTRUMENTS 128
      • 5.2.1 TRADITIONAL THERMOCYCLER 132
      • 5.2.2 REAL TIME THERMOCYCLER 134
    • 5.3 REAGENTS AND CONSUMABLES 136
      • 5.3.1 ENZYMES 141
      • 5.3.2 DEOXYNUCLEOTIDE TRIPHOSPHATE'S (DNTP'S) 144
      • 5.3.3 TEMPLATES OR CONTROLS 146
      • 5.3.4 PRIMERS AND PROBES 148
      • 5.3.5 BUFFERS 150
      • 5.3.6 REAGENT KITS OR MASTER MIXES 152
      • 5.3.7 NUCLEASE FREE WATER 154
      • 5.3.8 CONSUMABLES 156
      • 5.3.9 OTHER REAGENTS AND CONSUMABLES 158
    • 5.4 SOFTWARE & SERVICES 160

    6 PCR GLOBAL MARKET, BY APPLICATION 166

    • 6.1 INTRODUCTION 166
    • 6.2 CLINICAL DIAGNOSTICS 169
      • 6.2.1 INFECTIOUS DISEASES 174
        • 6.2.1.1 Hepatitis B and C testing 178
        • 6.2.1.2 Tuberculosis diagnosis 181
        • 6.2.1.3 HIV diagnosis 184
        • 6.2.1.4 Other infectious disease 186
      • 6.2.2 NON-INFECTIOUS DISEASES 188
        • 6.2.2.1 Prenatal diagnosis 193
        • 6.2.2.2 Tissue typing/transplant 195
        • 6.2.2.3 Cancer therapy 197
        • 6.2.2.4 Genetic testing for hereditary diseases 200
        • 6.2.2.5 Blood screening 202
        • 6.2.2.6 Other non-infectious applications 204
    • 6.3 INDUSTRIAL APPLICATIONS 206
      • 6.3.1 AGRICULTURE 211
      • 6.3.2 ENVIRONMENT 215
      • 6.3.3 APPLIED TESTING 218
        • 6.3.3.1 Forensics 222
        • 6.3.3.2 Food safety testing 225
      • 6.3.4 ANIMAL HUSBANDRY 228
      • 6.3.5 BIOMEDICAL RESEARCH 232
        • 6.3.5.1 DNA sequencing 237
        • 6.3.5.2 Genotyping 239
        • 6.3.5.3 Biomarker discovery 242
        • 6.3.5.4 Gene expression and genetic mapping 244
        • 6.3.5.5 DNA cloning 246
        • 6.3.5.6 Other biomedical research applications 248
      • 6.3.6 OTHER PCR INDUSTRY APPLICATIONS 250
    • 6.4 OTHER PCR APPLICATIONS 252

    7 PCR GLOBAL MARKET, BY END-USERS 255

    • 7.1 INTRODUCTION 255
    • 7.2 HOSPITALS AND LABORATORIES 258
    • 7.3 PHARMACEUTICALS, CRO'S AND BIOTECH 261
    • 7.4 ACADEMICS 264
    • 7.5 OTHER PCR END USERS 266

    8 REGIONAL ANALYSIS 269

    • 8.1 INTRODUCTION 269
    • 8.2 NORTH AMERICA 273
      • 8.2.1 U.S. 293
      • 8.2.2 REST OF NORTH AMERICA 298
    • 8.3 EUROPE 303
      • 8.3.1 GERMANY 325
      • 8.3.2 U.K. 329
      • 8.3.3 FRANCE 333
      • 8.3.4 REST OF EUROPE 337
    • 8.4 APAC 341
      • 8.4.1 CHINA 362
      • 8.4.2 JAPAN 366
      • 8.4.3 INDIA 369
      • 8.4.4 REST OF APAC 372
    • 8.5 ROW 375
      • 8.5.1 BRAZIL 395
      • 8.5.2 REST OF LATAM 399
      • 8.5.3 MIDDLE EAST & OTHERS 402

    9 COMPETITIVE LANDSCAPE 405

    • 9.1 INTRODUCTION 405
    • 9.2 APPROVALS 406
    • 9.3 NEW PRODUCT LAUNCH 411
    • 9.4 ACQUISITION, AGREEMENTS AND PARTNERSHIP 417
    • 9.5 OTHERS 420

    10 MAJOR COMPANIES 421

    • 10.1 ABBOTT LABORATORIES, INC. 421
      • 10.1.1 OVERVIEW 421
      • 10.1.2 FINANCIALS 422
      • 10.1.3 PRODUCT PORTFOLIO 426
      • 10.1.4 KEY DEVELOPMENTS 427
      • 10.1.5 BUSINESS STRATEGY 428
      • 10.1.6 SWOT ANALYSIS 429
    • 10.2 AGILENT TECHNOLOGIES 430
      • 10.2.1 OVERVIEW 430
      • 10.2.2 FINANCIALS 431
      • 10.2.3 PRODUCT PORTFOLIO 434
      • 10.2.4 KEY DEVELOPMENTS 437
      • 10.2.5 BUSINESS STRATEGY 437
      • 10.2.6 SWOT ANALYSIS 438
    • 10.3 BECTON DICKINSON AND COMPANY 439
      • 10.3.1 OVERVIEW 439
      • 10.3.2 FINANCIALS 440
      • 10.3.3 PRODUCT PORTFOLIO 444
      • 10.3.4 KEY DEVELOPMENTS 444
      • 10.3.5 BUSINESS STRATEGY 445
      • 10.3.6 SWOT ANALYSIS 446
    • 10.4 BIOMERIEUX SA 447
      • 10.4.1 OVERVIEW 447
      • 10.4.2 FINANCIALS 448
      • 10.4.3 PRODUCT PORTFOLIO 451
      • 10.4.4 KEY DEVELOPMENSTS 452
      • 10.4.5 BUSINESS STRATEGY 453
      • 10.4.6 SWOT ANALYSIS 454
    • 10.5 BIO-RAD LABORATORIES 455
      • 10.5.1 OVERVIEW 455
      • 10.5.2 FINANCIALS 456
      • 10.5.3 PRODUCT PORTFOLIO 459
      • 10.5.4 KEY DEVELOPMENTS 462
      • 10.5.5 BUSINESS STRATEGY 464
      • 10.5.6 SWOT ANALYSIS 465
    • 10.6 F.HOFFMANN-LA ROCHE LTD (ROCHE DIAGNOSTICS) 466
      • 10.6.1 OVERVIEW 466
      • 10.6.2 FINANCIALS 467
      • 10.6.3 PRODUCT PORTFOLIO 471
      • 10.6.4 KEY DEVELOPMENTS 473
      • 10.6.5 BUSINESS STRATEGY 475
      • 10.6.6 SWOT ANALYSIS 476
    • 10.7 GENERAL ELECTRIC COMPANY (GE HEALTHCARE) 477
      • 10.7.1 OVERVIEW 477
      • 10.7.2 FINANCIALS 478
      • 10.7.3 PRODUCT PORTFOLIO 481
      • 10.7.4 KEY DEVELOPMENTS 482
      • 10.7.5 BUSINESS STRATEGY 482
      • 10.7.6 SWOT ANALYSIS 483
    • 10.8 MERCK KGAA 484
      • 10.8.1 OVERVIEW 484
      • 10.8.2 FINANCIALS 485
      • 10.8.3 PRODUCT PORTFOLIO 488
      • 10.8.4 KEY DEVELOPMENTS 491
      • 10.8.5 BUSINESS STRATEGY 491
      • 10.8.6 SWOT ANALYSIS 492
    • 10.9 PROMEGA CORPORATION 493
      • 10.9.1 OVERVIEW 493
      • 10.9.2 FINANCIALS 494
      • 10.9.3 PRODUCT PORTFOLIO 494
      • 10.9.4 KEY DEVELOPMENTS 496
      • 10.9.5 BUSINESS STRATEGY 498
      • 10.9.6 SWOT ANALYSIS 499
    • 10.10 QIAGEN N.V. 500
      • 10.10.1 OVERVIEW 500
      • 10.10.2 FINANCIALS 501
      • 10.10.3 PRODUCT PORTFOLIO 505
      • 10.10.4 KEY DEVELOPMENTS 506
      • 10.10.5 BUSINESS STRATEGY 510
      • 10.10.6 SWOT ANALYSIS 511
    • 10.11 TAKARA BIO, INC. 512
      • 10.11.1 OVERVIEW 512
      • 10.11.2 FINANCIALS 513
      • 10.11.3 PRODUCT PORTFOLIO 516
      • 10.11.4 KEY DEVELOPMENTS 518
      • 10.11.5 BUSINESS STRATEGY 519
      • 10.11.6 SWOT ANALYSIS 520
    • 10.12 THERMO FISHER SCIENTIFIC, INC. 521
      • 10.12.1 OVERVIEW 521
      • 10.12.2 FINANCIALS 522
      • 10.12.3 PRODUCT PORTFOLIO 525
      • 10.12.4 KEY DEVELOPMENTS 528
      • 10.12.5 BUSINESS STRATEGY 530

    Polymerase Chain Reaction (PCR) is a novel technique which amplifies the amount of target nucleic acid in every cycle. PCR has three steps such as denaturation, annealing and extension, which are repeated in every cycle to achieve the product. The PCR market is expected to reach $12,910.1 million by 2025 growing at a high single digit CAGR from 2019 to 2025. PCR market is segmented based on techniques, products, applications, end users and geography.
    The factors driving the growth of PCR market are increasing demand for early detection of chronic diseases, increasing demand for genetic and molecular testing, high prevalence of infectious diseases, expiry of PCR patents of major players, increased investments in the field of companion diagnostics using PCR, increasing qPCR based food safety testing, technological advancements and growing demand for rapid diagnostic tests. However, factors like high cost of commercial PCR assays in clinical diagnostics, lack of awareness and requirement of skilled labor, development of alternate technologies and stringent regulatory framework are hampering the market.
    By Technique, the PCR market is segmented into standard PCR, real time PCR, reverse transcriptase PCR, digital PCR, assembly PCR, multiplex PCR, Hot start PCR and others. Others include nested PCR, Inverse PCR, Immune PCR, anchored PCR, RACE PCR, asymmetric PCR, universal PCR, ISSR PCR, allele specific PCR, ligation mediated PCR, touchdown PCR, solid phase PCR, methylation PCR, miniprimer PCR, nanoparticle assisted PCR, overlap extension PCR and In-situ PCR and long PCR. Among PCR Techniques, RealTime/qPCR segment accounted for the largest revenue in 2019 and is expected to grow at a high single digit CAGR from 2019 to 2025. The digital PCR segment is the fastest growing market in 2019 and is expected grow at a low double digit CAGR from 2019 to 2025.
    The PCR global market by product is segmented into instruments, reagents and consumables and software and services, among the products Reagents and consumables accounted for largest revenue in 2019 and is expected to grow at a high single digit CAGR from 2019 to 2025. The instruments segment is classified as traditional PCR’s and Real time PCR’s. Reagents and consumables are sub segmented into enzymes, dNTPs, template DNA, primers and probes, buffers, master mixes, nuclease free water, consumable and others (tracking dye and wax beads). Software’s in the PCR market include Primer designers and sequence software’s, PCR data analysis software and others.
    By application, the market is segmented into clinical diagnostics, industrial application, and others. Clinical diagnostics segment is further divided into infectious and non infectious diseases. Infectious disease includes hepatitis B & C, tuberculosis, HIV and others. Non infectious diseases include prenatal diagnosis, tissue typing, cancer therapy, genetic typing for hereditary disease, blood screening and others. Industrial applications are divided into Agricultural, Environment, Applied testing, Animal husbandry, biomedical research and other PCR industry applications. Applied testing includes forensic and food safety testing. Biomedical research includes DNA sequencing, genotyping, biomarker discovery, gene expression and genetic mapping, DNA cloning and others. In PCR applications market, the industry segment accounted for the largest revenue in 2019 and is expected to grow at a high single digit CAGR from 2019 to 2025 and the clinical diagnosis segment is the fastest growing market in 2019 and is expected to grow at a high single digit CAGR from 2019 to 2025.
    By end- users, Academics accounted for the largest revenue in 2019 and is expected to grow at a high single digit CAGR from 2019 to 2025 and The Hospitals & laboratories segment is the fastest growing market in 2019 and is expected to grow at a high single digit CAGR from 2019 to 2025. Geographically, North America accounted for largest revenue in 2019 and it is expected to grow at a high single digit CAGR from 2019 to 2025 and The APAC region is the fastest growing market in 2019 and is expected to grow at a high single digit CAGR from 2019 to 2025.
    Some of the major players in the PCR market are ThermoFisher Scientific, Inc. (U.S.), Abbott Laboratories, Inc. (U.S.), Agilent Technologies (U.S.), Becton, Dickinson and Company (U.S.), BioMerieux SA (France), Bio-Rad Laboratories, Inc. (U.S.), GE Healthcare (U.S.), Hoffmann la Roche (Switzerland), Merck KGaA (Germany), Promega Corporation (U.S.), Qiagen N.V. (Netherlands) and Takara Bio, Inc.(Japan).
    The report provides an in-depth market analysis of the above-mentioned segments across the following regions:
    • North America
    o U.S.
    o Rest of North America
    • Europe
    o Germany
    o U.K.
    o France
    o Rest of Europe
    • Asia-Pacific
    o China
    o Japan
    o India
    o Rest of APAC
    • Rest of the World (RoW)
    o Brazil
    o Rest of Latin America
    o Middle East and Others


    Summary:
    Get latest Market Research Reports on Polymerase Chain Reaction (PCR). Industry analysis & Market Report on Polymerase Chain Reaction (PCR) is a syndicated market report, published as Polymerase Chain Reaction (PCR) Global Market - Forecast to 2025. It is complete Research Study and Industry Analysis of Polymerase Chain Reaction (PCR) market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.

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