Report Detail

Pharmaceuticals & Healthcare Narcolepsy - Pipeline Review, H2 2018

  • RnM2474168
  • |
  • 11 October, 2018
  • |
  • Global
  • |
  • 86 Pages
  • |
  • Global Markets Direct
  • |
  • Pharmaceuticals & Healthcare

Table of Contents

    List of Tables

      List of Figures

        Introduction

          Global Markets Direct Report Coverage

            Narcolepsy - Overview

              Narcolepsy - Therapeutics Development

                Pipeline Overview

                  Pipeline by Companies

                    Pipeline by Universities/Institutes

                      Products under Development by Companies

                        Products under Development by Universities/Institutes

                          Narcolepsy - Therapeutics Assessment

                            Assessment by Target

                              Assessment by Mechanism of Action

                                Assessment by Route of Administration

                                  Assessment by Molecule Type

                                    Narcolepsy - Companies Involved in Therapeutics Development

                                      Avadel Pharmaceuticals Plc

                                        Axsome Therapeutics Inc

                                          Balance Therapeutics Inc

                                            Bioprojet SCR

                                              F. Hoffmann-La Roche Ltd

                                                Inexia Ltd

                                                  Jazz Pharmaceuticals Plc

                                                    NLS Pharma Group

                                                      Ono Pharmaceutical Co Ltd

                                                        Orexia Ltd

                                                          Seelos Therapeutics, Inc.

                                                            Suven Life Sciences Ltd

                                                              Takeda Pharmaceutical Co Ltd

                                                                Theranexus SAS

                                                                  Vallon Pharmaceuticals Inc

                                                                    XW Laboratories Inc

                                                                      Narcolepsy - Drug Profiles

                                                                        (flecainide acetate + modafinil) - Drug Profile

                                                                          Product Description

                                                                            Mechanism Of Action

                                                                              R&D Progress

                                                                                arbaclofen - Drug Profile

                                                                                  Product Description

                                                                                    Mechanism Of Action

                                                                                      R&D Progress

                                                                                        dextroamphetamine IR - Drug Profile

                                                                                          Product Description

                                                                                            Mechanism Of Action

                                                                                              R&D Progress

                                                                                                JZP-258 - Drug Profile

                                                                                                  Product Description

                                                                                                    Mechanism Of Action

                                                                                                      R&D Progress

                                                                                                        mazindol - Drug Profile

                                                                                                          Product Description

                                                                                                            Mechanism Of Action

                                                                                                              R&D Progress

                                                                                                                NLS-4 - Drug Profile

                                                                                                                  Product Description

                                                                                                                    Mechanism Of Action

                                                                                                                      R&D Progress

                                                                                                                        ONO-4127 - Drug Profile

                                                                                                                          Product Description

                                                                                                                            Mechanism Of Action

                                                                                                                              R&D Progress

                                                                                                                                OPN-021 - Drug Profile

                                                                                                                                  Product Description

                                                                                                                                    Mechanism Of Action

                                                                                                                                      R&D Progress

                                                                                                                                        Oxybate - Drug Profile

                                                                                                                                          Product Description

                                                                                                                                            Mechanism Of Action

                                                                                                                                              R&D Progress

                                                                                                                                                pentylenetetrazol - Drug Profile

                                                                                                                                                  Product Description

                                                                                                                                                    Mechanism Of Action

                                                                                                                                                      R&D Progress

                                                                                                                                                        pitolisant hydrochloride - Drug Profile

                                                                                                                                                          Product Description

                                                                                                                                                            Mechanism Of Action

                                                                                                                                                              R&D Progress

                                                                                                                                                                reboxetine - Drug Profile

                                                                                                                                                                  Product Description

                                                                                                                                                                    Mechanism Of Action

                                                                                                                                                                      R&D Progress

                                                                                                                                                                        RO-5256390 - Drug Profile

                                                                                                                                                                          Product Description

                                                                                                                                                                            Mechanism Of Action

                                                                                                                                                                              R&D Progress

                                                                                                                                                                                SLS-010 - Drug Profile

                                                                                                                                                                                  Product Description

                                                                                                                                                                                    Mechanism Of Action

                                                                                                                                                                                      R&D Progress

                                                                                                                                                                                        Small Molecule to Agonize Orexin-2 for Narcolepsy and Sleep Disorders - Drug Profile

                                                                                                                                                                                          Product Description

                                                                                                                                                                                            Mechanism Of Action

                                                                                                                                                                                              R&D Progress

                                                                                                                                                                                                sodium oxybate ER - Drug Profile

                                                                                                                                                                                                  Product Description

                                                                                                                                                                                                    Mechanism Of Action

                                                                                                                                                                                                      R&D Progress

                                                                                                                                                                                                        SUVNG-3031 - Drug Profile

                                                                                                                                                                                                          Product Description

                                                                                                                                                                                                            Mechanism Of Action

                                                                                                                                                                                                              R&D Progress

                                                                                                                                                                                                                TAK-925 - Drug Profile

                                                                                                                                                                                                                  Product Description

                                                                                                                                                                                                                    Mechanism Of Action

                                                                                                                                                                                                                      R&D Progress

                                                                                                                                                                                                                        TAK-994 - Drug Profile

                                                                                                                                                                                                                          Product Description

                                                                                                                                                                                                                            Mechanism Of Action

                                                                                                                                                                                                                              R&D Progress

                                                                                                                                                                                                                                XWL-008 - Drug Profile

                                                                                                                                                                                                                                  Product Description

                                                                                                                                                                                                                                    Mechanism Of Action

                                                                                                                                                                                                                                      R&D Progress

                                                                                                                                                                                                                                        YNT-185 - Drug Profile

                                                                                                                                                                                                                                          Product Description

                                                                                                                                                                                                                                            Mechanism Of Action

                                                                                                                                                                                                                                              R&D Progress

                                                                                                                                                                                                                                                Narcolepsy - Dormant Projects

                                                                                                                                                                                                                                                  Narcolepsy - Discontinued Products

                                                                                                                                                                                                                                                    Narcolepsy - Product Development Milestones

                                                                                                                                                                                                                                                      Featured News & Press Releases

                                                                                                                                                                                                                                                        Mar 30, 2020: Harmony Biosciences highlights publication Of narcolepsy treatment scientific review in sleep medicine

                                                                                                                                                                                                                                                          Mar 25, 2020: Avadel Pharmaceuticals completes the REST-ON Phase 3 Pivotal trial of FT218 for Excessive Daytime Sleepiness and Cataplexy in Patients with Narcolepsy

                                                                                                                                                                                                                                                            Mar 25, 2020: Jazz Pharmaceuticals announces FDA acceptance of New Drug Application for JZP-258 for Cataplexy and Excessive Daytime Sleepiness Associated with Narcolepsy

                                                                                                                                                                                                                                                              Jan 22, 2020: Jazz Pharmaceuticals submits new drug application for JZP-258 for cataplexy and excessive daytime sleepiness associated with narcolepsy

                                                                                                                                                                                                                                                                Dec 17, 2019: Avadel Pharmaceuticals completes enrollment in the REST-ON Phase 3 Pivotal Trial of FT218 for Excessive Daytime Sleepiness and Cataplexy in Patients with Narcolepsy

                                                                                                                                                                                                                                                                  Dec 03, 2019: Axsome Therapeutics announces AXS-12 achieves primary endpoint in CONCERT phase 2 trial in Narcolepsy

                                                                                                                                                                                                                                                                    Dec 02, 2019: Avadel Pharmaceuticals announces key appointments to leadership team to support continued transformation and the advancement of FT218

                                                                                                                                                                                                                                                                      Nov 25, 2019: Avadel Pharmaceuticals achieves enrollment target in REST-ON phase 3 pivotal trial of FT218 for excessive daytime sleepiness and Cataplexy in patients with Narcolepsy

                                                                                                                                                                                                                                                                        Nov 20, 2019: Harmony Biosciences announces publication of data in sleep from two clinical studies of WAKIX (pitolisant)

                                                                                                                                                                                                                                                                          Oct 21, 2019: Axsome Therapeutics completes patient enrollment in the CONCERT Phase 2 trial of AXS-12 in narcolepsy

                                                                                                                                                                                                                                                                            Oct 02, 2019: Axsome Therapeutics to Provide Update on AXS-12 at the 2019 Cantor Global Healthcare Conference

                                                                                                                                                                                                                                                                              Sep 26, 2019: New data presented on TAK-994, an oral selective OX2R agonist at World Sleep Congress

                                                                                                                                                                                                                                                                                Sep 26, 2019: New data presented at World Sleep Congress demonstrate early signs of efficacy for TAK-925,, a selective orexin type-2 receptor (OX2R) agonist, in patients with narcolepsy type 1

                                                                                                                                                                                                                                                                                  Sep 25, 2019: Jazz Pharmaceuticals presents positive JZP-258 phase 3 study data at World Sleep 2019

                                                                                                                                                                                                                                                                                    Sep 24, 2019: First patient randomized in a Phase 2A, Proof of Concept (PoC) clinical trial of SUVN-G3031 for the treatment of Narcolepsy associated with or without Cataplexy in USA

                                                                                                                                                                                                                                                                                      Appendix

                                                                                                                                                                                                                                                                                        Methodology

                                                                                                                                                                                                                                                                                          Coverage

                                                                                                                                                                                                                                                                                            Secondary Research

                                                                                                                                                                                                                                                                                              Primary Research

                                                                                                                                                                                                                                                                                                Expert Panel Validation

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                                                                                                                                                                                                                                                                                                    Disclaimer

                                                                                                                                                                                                                                                                                                    Narcolepsy - Pipeline Review, H1 2020

                                                                                                                                                                                                                                                                                                    Summary

                                                                                                                                                                                                                                                                                                    Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Narcolepsy - Pipeline Review, H1 2020, provides an overview of the Narcolepsy (Central Nervous System) pipeline landscape.

                                                                                                                                                                                                                                                                                                    Narcolepsy is a sleep disorder that causes excessive sleepiness and frequent daytime sleep attacks. Symptoms of narcolepsy include excessive daytime sleepiness (EDS), cataplexy, hallucinations and sleep paralysis. Narcolepsy treatment includes lifestyle change, medication and counseling.

                                                                                                                                                                                                                                                                                                    Report Highlights

                                                                                                                                                                                                                                                                                                    Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Narcolepsy - Pipeline Review, H1 2020, provides comprehensive information on the therapeutics under development for Narcolepsy (Central Nervous System), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

                                                                                                                                                                                                                                                                                                    The Narcolepsy (Central Nervous System) pipeline guide also reviews of key players involved in therapeutic development for Narcolepsy and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 1, 6, 4, 6 and 1 respectively. Similarly, the Universities portfolio in Preclinical stages comprises 2 molecules, respectively.

                                                                                                                                                                                                                                                                                                    Narcolepsy (Central Nervous System) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

                                                                                                                                                                                                                                                                                                    Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

                                                                                                                                                                                                                                                                                                    Scope

                                                                                                                                                                                                                                                                                                    - The pipeline guide provides a snapshot of the global therapeutic landscape of Narcolepsy (Central Nervous System).
                                                                                                                                                                                                                                                                                                    - The pipeline guide reviews pipeline therapeutics for Narcolepsy (Central Nervous System) by companies and universities/research institutes based on information derived from company and industry-specific sources.
                                                                                                                                                                                                                                                                                                    - The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
                                                                                                                                                                                                                                                                                                    - The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
                                                                                                                                                                                                                                                                                                    - The pipeline guide reviews key companies involved in Narcolepsy (Central Nervous System) therapeutics and enlists all their major and minor projects.
                                                                                                                                                                                                                                                                                                    - The pipeline guide evaluates Narcolepsy (Central Nervous System) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
                                                                                                                                                                                                                                                                                                    - The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
                                                                                                                                                                                                                                                                                                    - The pipeline guide reviews latest news related to pipeline therapeutics for Narcolepsy (Central Nervous System)

                                                                                                                                                                                                                                                                                                    Reasons to Buy

                                                                                                                                                                                                                                                                                                    - Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
                                                                                                                                                                                                                                                                                                    - Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
                                                                                                                                                                                                                                                                                                    - Find and recognize significant and varied types of therapeutics under development for Narcolepsy (Central Nervous System).
                                                                                                                                                                                                                                                                                                    - Classify potential new clients or partners in the target demographic.
                                                                                                                                                                                                                                                                                                    - Develop tactical initiatives by understanding the focus areas of leading companies.
                                                                                                                                                                                                                                                                                                    - Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
                                                                                                                                                                                                                                                                                                    - Formulate corrective measures for pipeline projects by understanding Narcolepsy (Central Nervous System) pipeline depth and focus of Indication therapeutics.
                                                                                                                                                                                                                                                                                                    - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
                                                                                                                                                                                                                                                                                                    - Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.


                                                                                                                                                                                                                                                                                                    Summary:
                                                                                                                                                                                                                                                                                                    Get latest Market Research Reports on Narcolepsy. Industry analysis & Market Report on Narcolepsy is a syndicated market report, published as Narcolepsy - Pipeline Review, H2 2018. It is complete Research Study and Industry Analysis of Narcolepsy market, to understand, Market Demand, Growth, trends analysis and Factor Influencing market.

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