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Global Methotrexate Market 2025 by Manufacturers, Regions, Type and Application, Forecast to 2031

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1 Market Overview

  • 1.1 Product Overview and Scope
  • 1.2 Market Estimation Caveats and Base Year
  • 1.3 Market Analysis by Type
    • 1.3.1 Overview: Global Methotrexate Consumption Value by Type: 2020 Versus 2024 Versus 2031
    • 1.3.2 Methotrexate for Injection
    • 1.3.3 Methotrexate Tablets
  • 1.4 Market Analysis by Application
    • 1.4.1 Overview: Global Methotrexate Consumption Value by Application: 2020 Versus 2024 Versus 2031
    • 1.4.2 Used for Cancers
    • 1.4.3 Used for Rheumatoid Arthritis
    • 1.4.4 Used for Other Diseases
  • 1.5 Global Methotrexate Market Size & Forecast
    • 1.5.1 Global Methotrexate Consumption Value (2020 & 2024 & 2031)
    • 1.5.2 Global Methotrexate Sales Quantity (2020-2031)
    • 1.5.3 Global Methotrexate Average Price (2020-2031)

2 Manufacturers Profiles

  • 2.1 Teva Pharmaceutical Industries
    • 2.1.1 Teva Pharmaceutical Industries Details
    • 2.1.2 Teva Pharmaceutical Industries Major Business
    • 2.1.3 Teva Pharmaceutical Industries Methotrexate Product and Services
    • 2.1.4 Teva Pharmaceutical Industries Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.1.5 Teva Pharmaceutical Industries Recent Developments/Updates
  • 2.2 Qualitestrx (DAVA Pharmaceuticals)
    • 2.2.1 Qualitestrx (DAVA Pharmaceuticals) Details
    • 2.2.2 Qualitestrx (DAVA Pharmaceuticals) Major Business
    • 2.2.3 Qualitestrx (DAVA Pharmaceuticals) Methotrexate Product and Services
    • 2.2.4 Qualitestrx (DAVA Pharmaceuticals) Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.2.5 Qualitestrx (DAVA Pharmaceuticals) Recent Developments/Updates
  • 2.3 Pfizer (Hospira)
    • 2.3.1 Pfizer (Hospira) Details
    • 2.3.2 Pfizer (Hospira) Major Business
    • 2.3.3 Pfizer (Hospira) Methotrexate Product and Services
    • 2.3.4 Pfizer (Hospira) Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.3.5 Pfizer (Hospira) Recent Developments/Updates
  • 2.4 Roxane Laboratories
    • 2.4.1 Roxane Laboratories Details
    • 2.4.2 Roxane Laboratories Major Business
    • 2.4.3 Roxane Laboratories Methotrexate Product and Services
    • 2.4.4 Roxane Laboratories Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.4.5 Roxane Laboratories Recent Developments/Updates
  • 2.5 Sine
    • 2.5.1 Sine Details
    • 2.5.2 Sine Major Business
    • 2.5.3 Sine Methotrexate Product and Services
    • 2.5.4 Sine Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.5.5 Sine Recent Developments/Updates
  • 2.6 Maoxiang
    • 2.6.1 Maoxiang Details
    • 2.6.2 Maoxiang Major Business
    • 2.6.3 Maoxiang Methotrexate Product and Services
    • 2.6.4 Maoxiang Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.6.5 Maoxiang Recent Developments/Updates
  • 2.7 LingNan Pharmaceutical
    • 2.7.1 LingNan Pharmaceutical Details
    • 2.7.2 LingNan Pharmaceutical Major Business
    • 2.7.3 LingNan Pharmaceutical Methotrexate Product and Services
    • 2.7.4 LingNan Pharmaceutical Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.7.5 LingNan Pharmaceutical Recent Developments/Updates
  • 2.8 Powerdone
    • 2.8.1 Powerdone Details
    • 2.8.2 Powerdone Major Business
    • 2.8.3 Powerdone Methotrexate Product and Services
    • 2.8.4 Powerdone Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.8.5 Powerdone Recent Developments/Updates
  • 2.9 Huiyu
    • 2.9.1 Huiyu Details
    • 2.9.2 Huiyu Major Business
    • 2.9.3 Huiyu Methotrexate Product and Services
    • 2.9.4 Huiyu Methotrexate Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
    • 2.9.5 Huiyu Recent Developments/Updates

3 Competitive Environment: Methotrexate by Manufacturer

  • 3.1 Global Methotrexate Sales Quantity by Manufacturer (2020-2025)
  • 3.2 Global Methotrexate Revenue by Manufacturer (2020-2025)
  • 3.3 Global Methotrexate Average Price by Manufacturer (2020-2025)
  • 3.4 Market Share Analysis (2024)
    • 3.4.1 Producer Shipments of Methotrexate by Manufacturer Revenue ($MM) and Market Share (%): 2024
    • 3.4.2 Top 3 Methotrexate Manufacturer Market Share in 2024
    • 3.4.3 Top 6 Methotrexate Manufacturer Market Share in 2024
  • 3.5 Methotrexate Market: Overall Company Footprint Analysis
    • 3.5.1 Methotrexate Market: Region Footprint
    • 3.5.2 Methotrexate Market: Company Product Type Footprint
    • 3.5.3 Methotrexate Market: Company Product Application Footprint
  • 3.6 New Market Entrants and Barriers to Market Entry
  • 3.7 Mergers, Acquisition, Agreements, and Collaborations

4 Consumption Analysis by Region

  • 4.1 Global Methotrexate Market Size by Region
    • 4.1.1 Global Methotrexate Sales Quantity by Region (2020-2031)
    • 4.1.2 Global Methotrexate Consumption Value by Region (2020-2031)
    • 4.1.3 Global Methotrexate Average Price by Region (2020-2031)
  • 4.2 North America Methotrexate Consumption Value (2020-2031)
  • 4.3 Europe Methotrexate Consumption Value (2020-2031)
  • 4.4 Asia-Pacific Methotrexate Consumption Value (2020-2031)
  • 4.5 South America Methotrexate Consumption Value (2020-2031)
  • 4.6 Middle East & Africa Methotrexate Consumption Value (2020-2031)

5 Market Segment by Type

  • 5.1 Global Methotrexate Sales Quantity by Type (2020-2031)
  • 5.2 Global Methotrexate Consumption Value by Type (2020-2031)
  • 5.3 Global Methotrexate Average Price by Type (2020-2031)

6 Market Segment by Application

  • 6.1 Global Methotrexate Sales Quantity by Application (2020-2031)
  • 6.2 Global Methotrexate Consumption Value by Application (2020-2031)
  • 6.3 Global Methotrexate Average Price by Application (2020-2031)

7 North America

  • 7.1 North America Methotrexate Sales Quantity by Type (2020-2031)
  • 7.2 North America Methotrexate Sales Quantity by Application (2020-2031)
  • 7.3 North America Methotrexate Market Size by Country
    • 7.3.1 North America Methotrexate Sales Quantity by Country (2020-2031)
    • 7.3.2 North America Methotrexate Consumption Value by Country (2020-2031)
    • 7.3.3 United States Market Size and Forecast (2020-2031)
    • 7.3.4 Canada Market Size and Forecast (2020-2031)
    • 7.3.5 Mexico Market Size and Forecast (2020-2031)

8 Europe

  • 8.1 Europe Methotrexate Sales Quantity by Type (2020-2031)
  • 8.2 Europe Methotrexate Sales Quantity by Application (2020-2031)
  • 8.3 Europe Methotrexate Market Size by Country
    • 8.3.1 Europe Methotrexate Sales Quantity by Country (2020-2031)
    • 8.3.2 Europe Methotrexate Consumption Value by Country (2020-2031)
    • 8.3.3 Germany Market Size and Forecast (2020-2031)
    • 8.3.4 France Market Size and Forecast (2020-2031)
    • 8.3.5 United Kingdom Market Size and Forecast (2020-2031)
    • 8.3.6 Russia Market Size and Forecast (2020-2031)
    • 8.3.7 Italy Market Size and Forecast (2020-2031)

9 Asia-Pacific

  • 9.1 Asia-Pacific Methotrexate Sales Quantity by Type (2020-2031)
  • 9.2 Asia-Pacific Methotrexate Sales Quantity by Application (2020-2031)
  • 9.3 Asia-Pacific Methotrexate Market Size by Region
    • 9.3.1 Asia-Pacific Methotrexate Sales Quantity by Region (2020-2031)
    • 9.3.2 Asia-Pacific Methotrexate Consumption Value by Region (2020-2031)
    • 9.3.3 China Market Size and Forecast (2020-2031)
    • 9.3.4 Japan Market Size and Forecast (2020-2031)
    • 9.3.5 South Korea Market Size and Forecast (2020-2031)
    • 9.3.6 India Market Size and Forecast (2020-2031)
    • 9.3.7 Southeast Asia Market Size and Forecast (2020-2031)
    • 9.3.8 Australia Market Size and Forecast (2020-2031)

10 South America

  • 10.1 South America Methotrexate Sales Quantity by Type (2020-2031)
  • 10.2 South America Methotrexate Sales Quantity by Application (2020-2031)
  • 10.3 South America Methotrexate Market Size by Country
    • 10.3.1 South America Methotrexate Sales Quantity by Country (2020-2031)
    • 10.3.2 South America Methotrexate Consumption Value by Country (2020-2031)
    • 10.3.3 Brazil Market Size and Forecast (2020-2031)
    • 10.3.4 Argentina Market Size and Forecast (2020-2031)

11 Middle East & Africa

  • 11.1 Middle East & Africa Methotrexate Sales Quantity by Type (2020-2031)
  • 11.2 Middle East & Africa Methotrexate Sales Quantity by Application (2020-2031)
  • 11.3 Middle East & Africa Methotrexate Market Size by Country
    • 11.3.1 Middle East & Africa Methotrexate Sales Quantity by Country (2020-2031)
    • 11.3.2 Middle East & Africa Methotrexate Consumption Value by Country (2020-2031)
    • 11.3.3 Turkey Market Size and Forecast (2020-2031)
    • 11.3.4 Egypt Market Size and Forecast (2020-2031)
    • 11.3.5 Saudi Arabia Market Size and Forecast (2020-2031)
    • 11.3.6 South Africa Market Size and Forecast (2020-2031)

12 Market Dynamics

  • 12.1 Methotrexate Market Drivers
  • 12.2 Methotrexate Market Restraints
  • 12.3 Methotrexate Trends Analysis
  • 12.4 Porters Five Forces Analysis
    • 12.4.1 Threat of New Entrants
    • 12.4.2 Bargaining Power of Suppliers
    • 12.4.3 Bargaining Power of Buyers
    • 12.4.4 Threat of Substitutes
    • 12.4.5 Competitive Rivalry

13 Raw Material and Industry Chain

  • 13.1 Raw Material of Methotrexate and Key Manufacturers
  • 13.2 Manufacturing Costs Percentage of Methotrexate
  • 13.3 Methotrexate Production Process
  • 13.4 Industry Value Chain Analysis

14 Shipments by Distribution Channel

  • 14.1 Sales Channel
    • 14.1.1 Direct to End-User
    • 14.1.2 Distributors
  • 14.2 Methotrexate Typical Distributors
  • 14.3 Methotrexate Typical Customers

15 Research Findings and Conclusion

    16 Appendix

    • 16.1 Methodology
    • 16.2 Research Process and Data Source

    According to our (Global Info Research) latest study, the global Methotrexate market size was valued at US$ 561 million in 2024 and is forecast to a readjusted size of USD 672 million by 2031 with a CAGR of 2.6% during review period.
    Methotrexate is kwon as Amethopterin, Methotrexate Sodium, and MTX. It is a yellow or orange, crystalline powder, and made into methotrexate tablets and methotrexate for injection.
    Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. It may also be used to control juvenile rheumatoid arthritis.
    North America is the largest Methotrexate market with about 49% market share. China is follower, accounting for about 12% market share.
    The key players are Teva Pharmaceutical Industries, Qualitestrx(DAVA Pharmaceuticals), Pfizer (Hospira), Roxane Laboratories, Sine, Maoxiang, LingNan Pharmaceutical, Powerdone, Huiyu etc. Top 3 companies occupied about 65% market share.
    This report is a detailed and comprehensive analysis for global Methotrexate market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
    Key Features:
    Global Methotrexate market size and forecasts, in consumption value ($ Million), sales quantity (Kg), and average selling prices (USD/Kg), 2020-2031
    Global Methotrexate market size and forecasts by region and country, in consumption value ($ Million), sales quantity (Kg), and average selling prices (USD/Kg), 2020-2031
    Global Methotrexate market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (Kg), and average selling prices (USD/Kg), 2020-2031
    Global Methotrexate market shares of main players, shipments in revenue ($ Million), sales quantity (Kg), and ASP (USD/Kg), 2020-2025
    The Primary Objectives in This Report Are:
    To determine the size of the total market opportunity of global and key countries
    To assess the growth potential for Methotrexate
    To forecast future growth in each product and end-use market
    To assess competitive factors affecting the marketplace
    This report profiles key players in the global Methotrexate market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Teva Pharmaceutical Industries, Qualitestrx (DAVA Pharmaceuticals), Pfizer (Hospira), Roxane Laboratories, Sine, Maoxiang, LingNan Pharmaceutical, Powerdone, Huiyu, etc.
    This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
    Market Segmentation
    Methotrexate market is split by Type and by Application. For the period 2020-2031, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
    Market segment by Type
    Methotrexate for Injection
    Methotrexate Tablets
    Market segment by Application
    Used for Cancers
    Used for Rheumatoid Arthritis
    Used for Other Diseases
    Major players covered
    Teva Pharmaceutical Industries
    Qualitestrx (DAVA Pharmaceuticals)
    Pfizer (Hospira)
    Roxane Laboratories
    Sine
    Maoxiang
    LingNan Pharmaceutical
    Powerdone
    Huiyu
    Market segment by region, regional analysis covers
    North America (United States, Canada, and Mexico)
    Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
    Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
    South America (Brazil, Argentina, Colombia, and Rest of South America)
    Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
    The content of the study subjects, includes a total of 15 chapters:
    Chapter 1, to describe Methotrexate product scope, market overview, market estimation caveats and base year.
    Chapter 2, to profile the top manufacturers of Methotrexate, with price, sales quantity, revenue, and global market share of Methotrexate from 2020 to 2025.
    Chapter 3, the Methotrexate competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
    Chapter 4, the Methotrexate breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2020 to 2031.
    Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2020 to 2031.
    Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2020 to 2025.and Methotrexate market forecast, by regions, by Type, and by Application, with sales and revenue, from 2026 to 2031.
    Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
    Chapter 13, the key raw materials and key suppliers, and industry chain of Methotrexate.
    Chapter 14 and 15, to describe Methotrexate sales channel, distributors, customers, research findings and conclusion.

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